Jones AK - Search Results

1

Relationship between venetoclax exposure, rituximab coadministration, and progression-free survival in patients with relapsed or refractory chronic lymphocytic leukemia: demonstration of synergy.

Freise KJ, Jones AK, Menon RM, Verdugo ME, Humerickhouse RA, Awni WM, Salem AH. Freise KJ, et al. Among authors: jones ak. Hematol Oncol. 2017 Dec;35(4):679-684. doi: 10.1002/hon.2373. Epub 2016 Dec 16. Hematol Oncol. 2017. PMID: 27982454

2

Moving Beyond Maximum Tolerated Dose for Targeted Oncology Drugs: Use of Clinical Utility Index to Optimize Venetoclax Dosage in Multiple Myeloma Patients.

Freise KJ, Jones AK, Verdugo ME, Menon RM, Maciag PC, Salem AH. Freise KJ, et al. Among authors: jones ak. Clin Pharmacol Ther. 2017 Dec;102(6):970-976. doi: 10.1002/cpt.712. Epub 2017 May 26. Clin Pharmacol Ther. 2017. PMID: 28419431 Clinical Trial.

3

Clinical Predictors of Venetoclax Pharmacokinetics in Chronic Lymphocytic Leukemia and Non-Hodgkin's Lymphoma Patients: a Pooled Population Pharmacokinetic Analysis.

Jones AK, Freise KJ, Agarwal SK, Humerickhouse RA, Wong SL, Salem AH. Jones AK, et al. AAPS J. 2016 Sep;18(5):1192-1202. doi: 10.1208/s12248-016-9927-9. Epub 2016 May 27. AAPS J. 2016. PMID: 27233802 Clinical Trial.

4

Venetoclax does not prolong the QT interval in patients with hematological malignancies: an exposure-response analysis.

Freise KJ, Dunbar M, Jones AK, Hoffman D, Enschede SL, Wong S, Salem AH. Freise KJ, et al. Among authors: jones ak. Cancer Chemother Pharmacol. 2016 Oct;78(4):847-53. doi: 10.1007/s00280-016-3144-1. Epub 2016 Sep 1. Cancer Chemother Pharmacol. 2016. PMID: 27586967

5

Impact of Venetoclax Exposure on Clinical Efficacy and Safety in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia.

Freise KJ, Jones AK, Eckert D, Mensing S, Wong SL, Humerickhouse RA, Awni WM, Salem AH. Freise KJ, et al. Among authors: jones ak. Clin Pharmacokinet. 2017 May;56(5):515-523. doi: 10.1007/s40262-016-0453-9. Clin Pharmacokinet. 2017. PMID: 27638334 Clinical Trial.

6

Power Determination During Drug Development: Is Optimizing the Sample Size Based on Exposure-Response Analyses Underutilized?

Jones AK, Salem AH, Freise KJ. Jones AK, et al. CPT Pharmacometrics Syst Pharmacol. 2019 Mar;8(3):138-145. doi: 10.1002/psp4.12380. Epub 2019 Feb 5. CPT Pharmacometrics Syst Pharmacol. 2019. PMID: 30659774 Free PMC article.

7

No Need for Lopinavir Dose Adjustment during Pregnancy: a Population Pharmacokinetic and Exposure-Response Analysis in Pregnant and Nonpregnant HIV-Infected Subjects.

Salem AH, Jones AK, Santini-Oliveira M, Taylor GP, Patterson KB, Nilius AM, Klein CE. Salem AH, et al. Among authors: jones ak. Antimicrob Agents Chemother. 2015 Nov 2;60(1):400-8. doi: 10.1128/AAC.01197-15. Print 2016 Jan. Antimicrob Agents Chemother. 2015. PMID: 26525798 Free PMC article. Clinical Trial.

8

Population Pharmacokinetics of a Monthly Buprenorphine Depot Injection for the Treatment of Opioid Use Disorder: A Combined Analysis of Phase II and Phase III Trials.

Jones AK, Ngaimisi E, Gopalakrishnan M, Young MA, Laffont CM. Jones AK, et al. Clin Pharmacokinet. 2021 Apr;60(4):527-540. doi: 10.1007/s40262-020-00957-0. Epub 2020 Nov 2. Clin Pharmacokinet. 2021. PMID: 33135125 Free PMC article. Clinical Trial.

9

Black soldier fly (Diptera: Stratiomyidae) reduction of different sludges, subsequent safety, and research gaps.

Jones AK, Nur-Aliah NA, Ivorra T, Heo CC. Jones AK, et al. J Environ Manage. 2023 Oct 28;349:119394. doi: 10.1016/j.jenvman.2023.119394. Online ahead of print. J Environ Manage. 2023. PMID: 39491940 Review.

10

mARC1 Is the Main Contributor to Metabolic Reduction of N-Hydroxyurea.

Klopp C, Zhang X, Campbell MK, Kvaskoff D, Struwe MA, Warren CR, Bajrami B, Scheidig AJ, Jones AK, Clement B. Klopp C, et al. Among authors: jones ak. J Med Chem. 2024 Oct 24;67(20):18090-18097. doi: 10.1021/acs.jmedchem.4c01148. Epub 2024 Oct 13. J Med Chem. 2024. PMID: 39397364 Free PMC article.

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