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Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease.
Hanash AM, Dudakov JA, Hua G, O'Connor MH, Young LF, Singer NV, West ML, Jenq RR, Holland AM, Kappel LW, Ghosh A, Tsai JJ, Rao UK, Yim NL, Smith OM, Velardi E, Hawryluk EB, Murphy GF, Liu C, Fouser LA, Kolesnick R, Blazar BR, van den Brink MR. Hanash AM, et al. Among authors: velardi e. Immunity. 2012 Aug 24;37(2):339-50. doi: 10.1016/j.immuni.2012.05.028. Immunity. 2012. PMID: 22921121 Free PMC article.
Nrf2 regulates haematopoietic stem cell function.
Tsai JJ, Dudakov JA, Takahashi K, Shieh JH, Velardi E, Holland AM, Singer NV, West ML, Smith OM, Young LF, Shono Y, Ghosh A, Hanash AM, Tran HT, Moore MA, van den Brink MR. Tsai JJ, et al. Among authors: velardi e. Nat Cell Biol. 2013 Mar;15(3):309-16. doi: 10.1038/ncb2699. Epub 2013 Feb 24. Nat Cell Biol. 2013. PMID: 23434824 Free PMC article.
Adoptively transferred TRAIL+ T cells suppress GVHD and augment antitumor activity.
Ghosh A, Dogan Y, Moroz M, Holland AM, Yim NL, Rao UK, Young LF, Tannenbaum D, Masih D, Velardi E, Tsai JJ, Jenq RR, Penack O, Hanash AM, Smith OM, Piersanti K, Lezcano C, Murphy GF, Liu C, Palomba ML, Sauer MG, Sadelain M, Ponomarev V, van den Brink MR. Ghosh A, et al. Among authors: velardi e. J Clin Invest. 2013 Jun;123(6):2654-62. doi: 10.1172/JCI66301. Epub 2013 May 15. J Clin Invest. 2013. PMID: 23676461 Free PMC article.
WNT signaling suppression in the senescent human thymus.
Ferrando-Martínez S, Ruiz-Mateos E, Dudakov JA, Velardi E, Grillari J, Kreil DP, Muñoz-Fernandez MÁ, van den Brink MR, Leal M. Ferrando-Martínez S, et al. Among authors: velardi e. J Gerontol A Biol Sci Med Sci. 2015 Mar;70(3):273-81. doi: 10.1093/gerona/glu030. Epub 2014 Mar 22. J Gerontol A Biol Sci Med Sci. 2015. PMID: 24657825 Free PMC article.
Sex steroid blockade enhances thymopoiesis by modulating Notch signaling.
Velardi E, Tsai JJ, Holland AM, Wertheimer T, Yu VW, Zakrzewski JL, Tuckett AZ, Singer NV, West ML, Smith OM, Young LF, Kreines FM, Levy ER, Boyd RL, Scadden DT, Dudakov JA, van den Brink MR. Velardi E, et al. J Exp Med. 2014 Nov 17;211(12):2341-9. doi: 10.1084/jem.20131289. Epub 2014 Oct 20. J Exp Med. 2014. PMID: 25332287 Free PMC article.
Immune reconstitution following stem cell transplantation.
van den Brink MR, Velardi E, Perales MA. van den Brink MR, et al. Among authors: velardi e. Hematology Am Soc Hematol Educ Program. 2015;2015:215-9. doi: 10.1182/asheducation-2015.1.215. Hematology Am Soc Hematol Educ Program. 2015. PMID: 26637724 No abstract available.
Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration.
Lindemans CA, Calafiore M, Mertelsmann AM, O'Connor MH, Dudakov JA, Jenq RR, Velardi E, Young LF, Smith OM, Lawrence G, Ivanov JA, Fu YY, Takashima S, Hua G, Martin ML, O'Rourke KP, Lo YH, Mokry M, Romera-Hernandez M, Cupedo T, Dow L, Nieuwenhuis EE, Shroyer NF, Liu C, Kolesnick R, van den Brink MRM, Hanash AM. Lindemans CA, et al. Among authors: velardi e. Nature. 2015 Dec 24;528(7583):560-564. doi: 10.1038/nature16460. Epub 2015 Dec 9. Nature. 2015. PMID: 26649819 Free PMC article.
48 results