Altonsy MO - Search Results

1

Long-acting β₂-agonists promote glucocorticoid-mediated repression of NF-κB by enhancing expression of the feedback regulator TNFAIP3.

Altonsy MO, Mostafa MM, Gerber AN, Newton R. Altonsy MO, et al. Am J Physiol Lung Cell Mol Physiol. 2017 Mar 1;312(3):L358-L370. doi: 10.1152/ajplung.00426.2016. Epub 2016 Dec 29. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 28039105 Free PMC article.

2

The glucocorticoid receptor and KLF15 regulate gene expression dynamics and integrate signals through feed-forward circuitry.

Sasse SK, Mailloux CM, Barczak AJ, Wang Q, Altonsy MO, Jain MK, Haldar SM, Gerber AN. Sasse SK, et al. Among authors: altonsy mo. Mol Cell Biol. 2013 Jun;33(11):2104-15. doi: 10.1128/MCB.01474-12. Epub 2013 Mar 18. Mol Cell Biol. 2013. PMID: 23508109 Free PMC article.

3

Context-dependent cooperation between nuclear factor κB (NF-κB) and the glucocorticoid receptor at a TNFAIP3 intronic enhancer: a mechanism to maintain negative feedback control of inflammation.

Altonsy MO, Sasse SK, Phang TL, Gerber AN. Altonsy MO, et al. J Biol Chem. 2014 Mar 21;289(12):8231-9. doi: 10.1074/jbc.M113.545178. Epub 2014 Feb 5. J Biol Chem. 2014. PMID: 24500711 Free PMC article.

4

Cistrome Analysis of Glucocorticoid Receptor Activity in Bronchial Epithelial Cells Defines Novel Mechanisms of Steroid Efficacy.

Kadiyala V, Sasse SK, Altonsy MO, Phang TL, Gerber AN. Kadiyala V, et al. Among authors: altonsy mo. Ann Am Thorac Soc. 2016 Mar;13 Suppl 1(Suppl 1):S103. doi: 10.1513/AnnalsATS.201508-534MG. Ann Am Thorac Soc. 2016. PMID: 27027943 Free PMC article. No abstract available.

5

Cistrome-based Cooperation between Airway Epithelial Glucocorticoid Receptor and NF-κB Orchestrates Anti-inflammatory Effects.

Kadiyala V, Sasse SK, Altonsy MO, Berman R, Chu HW, Phang TL, Gerber AN. Kadiyala V, et al. Among authors: altonsy mo. J Biol Chem. 2016 Jun 10;291(24):12673-12687. doi: 10.1074/jbc.M116.721217. Epub 2016 Apr 13. J Biol Chem. 2016. PMID: 27076634 Free PMC article.

6

Glucocorticoid and TNF signaling converge at A20 (TNFAIP3) to repress airway smooth muscle cytokine expression.

Sasse SK, Altonsy MO, Kadiyala V, Cao G, Panettieri RA Jr, Gerber AN. Sasse SK, et al. Among authors: altonsy mo. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L421-32. doi: 10.1152/ajplung.00179.2016. Epub 2016 Jul 1. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 27371733 Free PMC article.

7

DUSP1 Maintains IRF1 and Leads to Increased Expression of IRF1-dependent Genes: A MECHANISM PROMOTING GLUCOCORTICOID INSENSITIVITY.

Shah S, King EM, Mostafa MM, Altonsy MO, Newton R. Shah S, et al. Among authors: altonsy mo. J Biol Chem. 2016 Oct 7;291(41):21802-21816. doi: 10.1074/jbc.M116.728964. Epub 2016 Aug 22. J Biol Chem. 2016. PMID: 27551049 Free PMC article.

8

Glucocorticoid and cytokine crosstalk: Feedback, feedforward, and co-regulatory interactions determine repression or resistance.

Newton R, Shah S, Altonsy MO, Gerber AN. Newton R, et al. Among authors: altonsy mo. J Biol Chem. 2017 Apr 28;292(17):7163-7172. doi: 10.1074/jbc.R117.777318. Epub 2017 Mar 10. J Biol Chem. 2017. PMID: 28283576 Free PMC article. Review.

9

Long-Acting β₂-Adrenoceptor Agonists Enhance Glucocorticoid Receptor (GR)-Mediated Transcription by Gene-Specific Mechanisms Rather Than Generic Effects via GR.

Rider CF, Altonsy MO, Mostafa MM, Shah SV, Sasse S, Manson ML, Yan D, Kärrman-Mårdh C, Miller-Larsson A, Gerber AN, Giembycz MA, Newton R. Rider CF, et al. Among authors: altonsy mo. Mol Pharmacol. 2018 Sep;94(3):1031-1046. doi: 10.1124/mol.118.112755. Epub 2018 Jun 29. Mol Pharmacol. 2018. PMID: 29959223 Free PMC article.

10

Corynebacterium tuberculostearicum, a human skin colonizer, induces the canonical nuclear factor-κB inflammatory signaling pathway in human skin cells.

Altonsy MO, Kurwa HA, Lauzon GJ, Amrein M, Gerber AN, Almishri W, Mydlarski PR. Altonsy MO, et al. Immun Inflamm Dis. 2020 Mar;8(1):62-79. doi: 10.1002/iid3.284. Epub 2020 Jan 7. Immun Inflamm Dis. 2020. PMID: 31912662 Free PMC article.

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