Chen SJ - Search Results

1

Characterization of Adeno-Associated Viral Vector-Mediated Human Factor VIII Gene Therapy in Hemophilia A Mice.

Greig JA, Wang Q, Reicherter AL, Chen SJ, Hanlon AL, Tipper CH, Clark KR, Wadsworth S, Wang L, Wilson JM. Greig JA, et al. Among authors: chen sj. Hum Gene Ther. 2017 May;28(5):392-402. doi: 10.1089/hum.2016.128. Epub 2017 Jan 5. Hum Gene Ther. 2017. PMID: 28056565

2

Evaluation of adeno-associated viral vectors for liver-directed gene transfer in dogs.

Bell P, Gao G, Haskins ME, Wang L, Sleeper M, Wang H, Calcedo R, Vandenberghe LH, Chen SJ, Weisse C, Withnall E, Wilson JM. Bell P, et al. Among authors: chen sj. Hum Gene Ther. 2011 Aug;22(8):985-97. doi: 10.1089/hum.2010.194. Epub 2011 Apr 11. Hum Gene Ther. 2011. PMID: 21204705 Free PMC article.

3

Enhancing the utility of adeno-associated virus gene transfer through inducible tissue-specific expression.

Chen SJ, Johnston J, Sandhu A, Bish LT, Hovhannisyan R, Jno-Charles O, Sweeney HL, Wilson JM. Chen SJ, et al. Hum Gene Ther Methods. 2013 Aug;24(4):270-8. doi: 10.1089/hgtb.2012.129. Hum Gene Ther Methods. 2013. PMID: 23895325 Free PMC article.

4

Biodistribution of AAV8 vectors expressing human low-density lipoprotein receptor in a mouse model of homozygous familial hypercholesterolemia.

Chen SJ, Sanmiguel J, Lock M, McMenamin D, Draper C, Limberis MP, Kassim SH, Somanathan S, Bell P, Johnston JC, Rader DJ, Wilson JM. Chen SJ, et al. Hum Gene Ther Clin Dev. 2013 Dec;24(4):154-60. doi: 10.1089/humc.2013.082. Epub 2013 Nov 9. Hum Gene Ther Clin Dev. 2013. PMID: 24070336 Free PMC article.

5

Absolute determination of single-stranded and self-complementary adeno-associated viral vector genome titers by droplet digital PCR.

Lock M, Alvira MR, Chen SJ, Wilson JM. Lock M, et al. Among authors: chen sj. Hum Gene Ther Methods. 2014 Apr;25(2):115-25. doi: 10.1089/hgtb.2013.131. Epub 2014 Feb 14. Hum Gene Ther Methods. 2014. PMID: 24328707 Free PMC article.

6

Intramuscular injection of AAV8 in mice and macaques is associated with substantial hepatic targeting and transgene expression.

Greig JA, Peng H, Ohlstein J, Medina-Jaszek CA, Ahonkhai O, Mentzinger A, Grant RL, Roy S, Chen SJ, Bell P, Tretiakova AP, Wilson JM. Greig JA, et al. Among authors: chen sj. PLoS One. 2014 Nov 13;9(11):e112268. doi: 10.1371/journal.pone.0112268. eCollection 2014. PLoS One. 2014. PMID: 25393537 Free PMC article.

7

Effects of Self-Complementarity, Codon Optimization, Transgene, and Dose on Liver Transduction with AAV8.

Bell P, Wang L, Chen SJ, Yu H, Zhu Y, Nayal M, He Z, White J, Lebel-Hagan D, Wilson JM. Bell P, et al. Among authors: chen sj. Hum Gene Ther Methods. 2016 Dec;27(6):228-237. doi: 10.1089/hgtb.2016.039. Hum Gene Ther Methods. 2016. PMID: 27903094 Free PMC article.

8

Nonclinical Pharmacology/Toxicology Study of AAV8.TBG.mLDLR and AAV8.TBG.hLDLR in a Mouse Model of Homozygous Familial Hypercholesterolemia.

Greig JA, Limberis MP, Bell P, Chen SJ, Calcedo R, Rader DJ, Wilson JM. Greig JA, et al. Among authors: chen sj. Hum Gene Ther Clin Dev. 2017 Mar;28(1):28-38. doi: 10.1089/humc.2017.007. Hum Gene Ther Clin Dev. 2017. PMID: 28319445 Free PMC article.

9

Non-Clinical Study Examining AAV8.TBG.hLDLR Vector-Associated Toxicity in Chow-Fed Wild-Type and LDLR^+/- Rhesus Macaques.

Greig JA, Limberis MP, Bell P, Chen SJ, Calcedo R, Rader DJ, Wilson JM. Greig JA, et al. Among authors: chen sj. Hum Gene Ther Clin Dev. 2017 Mar;28(1):39-50. doi: 10.1089/humc.2017.014. Hum Gene Ther Clin Dev. 2017. PMID: 28319449 Free PMC article.

10

Intranasal gene therapy to prevent infection by SARS-CoV-2 variants.

Sims JJ, Greig JA, Michalson KT, Lian S, Martino RA, Meggersee R, Turner KB, Nambiar K, Dyer C, Hinderer C, Horiuchi M, Yan H, Huang X, Chen SJ, Wilson JM. Sims JJ, et al. Among authors: chen sj. PLoS Pathog. 2021 Jul 15;17(7):e1009544. doi: 10.1371/journal.ppat.1009544. eCollection 2021 Jul. PLoS Pathog. 2021. PMID: 34265018 Free PMC article.

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