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Expanding the Solvent/Protein Region Occupation of the Non-Nucleoside Reverse Transcriptase Inhibitor Binding Pocket for Improved Broad-Spectrum Anti-HIV-1 Efficacy: from Rigid Phenyl-Diarylpyrimidines to Flexible Hydrophilic Piperidine-Diarylpyrimidines.
Huang WJ, Pannecouque C, De Clercq E, Corona A, Maloccu S, Tramontano E, Wang S, Chen FE. Huang WJ, et al. Among authors: wang s. J Med Chem. 2024 Nov 5. doi: 10.1021/acs.jmedchem.4c02413. Online ahead of print. J Med Chem. 2024. PMID: 39498544
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