Ali A - Search Results

1

Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism.

Hasan M, Gonugunta VK, Dobbs N, Ali A, Palchik G, Calvaruso MA, DeBerardinis RJ, Yan N. Hasan M, et al. Among authors: ali a. Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):746-751. doi: 10.1073/pnas.1611113114. Epub 2017 Jan 9. Proc Natl Acad Sci U S A. 2017. PMID: 28069950 Free PMC article.

2

Mutation of mouse Samd4 causes leanness, myopathy, uncoupled mitochondrial respiration, and dysregulated mTORC1 signaling.

Chen Z, Holland W, Shelton JM, Ali A, Zhan X, Won S, Tomisato W, Liu C, Li X, Moresco EM, Beutler B. Chen Z, et al. Among authors: ali a. Proc Natl Acad Sci U S A. 2014 May 20;111(20):7367-72. doi: 10.1073/pnas.1406511111. Epub 2014 May 5. Proc Natl Acad Sci U S A. 2014. PMID: 24799716 Free PMC article.

3

Metabolic reprogramming during TGFβ1-induced epithelial-to-mesenchymal transition.

Jiang L, Xiao L, Sugiura H, Huang X, Ali A, Kuro-o M, Deberardinis RJ, Boothman DA. Jiang L, et al. Among authors: ali a. Oncogene. 2015 Jul 23;34(30):3908-16. doi: 10.1038/onc.2014.321. Epub 2014 Oct 6. Oncogene. 2015. PMID: 25284588 Free PMC article.

4

NAMPT inhibition sensitizes pancreatic adenocarcinoma cells to tumor-selective, PAR-independent metabolic catastrophe and cell death induced by β-lapachone.

Moore Z, Chakrabarti G, Luo X, Ali A, Hu Z, Fattah FJ, Vemireddy R, DeBerardinis RJ, Brekken RA, Boothman DA. Moore Z, et al. Among authors: ali a. Cell Death Dis. 2015 Jan 15;6(1):e1599. doi: 10.1038/cddis.2014.564. Cell Death Dis. 2015. PMID: 25590809 Free PMC article.

5

Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone.

Chakrabarti G, Moore ZR, Luo X, Ilcheva M, Ali A, Padanad M, Zhou Y, Xie Y, Burma S, Scaglioni PP, Cantley LC, DeBerardinis RJ, Kimmelman AC, Lyssiotis CA, Boothman DA. Chakrabarti G, et al. Among authors: ali a. Cancer Metab. 2015 Oct 12;3:12. doi: 10.1186/s40170-015-0137-1. eCollection 2015. Cancer Metab. 2015. PMID: 26462257 Free PMC article.

6

Adipocyte Xbp1s overexpression drives uridine production and reduces obesity.

Deng Y, Wang ZV, Gordillo R, Zhu Y, Ali A, Zhang C, Wang X, Shao M, Zhang Z, Iyengar P, Gupta RK, Horton JD, Hill JA, Scherer PE. Deng Y, et al. Among authors: ali a. Mol Metab. 2018 May;11:1-17. doi: 10.1016/j.molmet.2018.02.013. Epub 2018 Mar 2. Mol Metab. 2018. PMID: 29551634 Free PMC article.

7

The estrogen-related receptor α inverse agonist XCT 790 is a nanomolar mitochondrial uncoupler.

Eskiocak B, Ali A, White MA. Eskiocak B, et al. Among authors: ali a. Biochemistry. 2014 Jul 29;53(29):4839-46. doi: 10.1021/bi500737n. Epub 2014 Jul 14. Biochemistry. 2014. PMID: 24999922 Free PMC article.

8

Pin1 null mice exhibit low bone mass and attenuation of BMP signaling.

Shen ZJ, Hu J, Ali A, Pastor J, Shiizaki K, Blank RD, Kuro-o M, Malter JS. Shen ZJ, et al. Among authors: ali a. PLoS One. 2013 May 10;8(5):e63565. doi: 10.1371/journal.pone.0063565. Print 2013. PLoS One. 2013. PMID: 23675491 Free PMC article.

9

Distinct regulatory mechanisms governing embryonic versus adult adipocyte maturation.

Wang QA, Tao C, Jiang L, Shao M, Ye R, Zhu Y, Gordillo R, Ali A, Lian Y, Holland WL, Gupta RK, Scherer PE. Wang QA, et al. Among authors: ali a. Nat Cell Biol. 2015 Sep;17(9):1099-111. doi: 10.1038/ncb3217. Epub 2015 Aug 17. Nat Cell Biol. 2015. PMID: 26280538 Free PMC article.

10

Fibulin-7, a heparin binding matricellular protein, promotes renal tubular calcification in mice.

Tsunezumi J, Sugiura H, Oinam L, Ali A, Thang BQ, Sada A, Yamashiro Y, Kuro-O M, Yanagisawa H. Tsunezumi J, et al. Among authors: ali a. Matrix Biol. 2018 Dec;74:5-20. doi: 10.1016/j.matbio.2018.04.014. Epub 2018 May 3. Matrix Biol. 2018. PMID: 29730503

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