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Page 1
Synergistic antileukemic therapies in NOTCH1-induced T-ALL.
Sanchez-Martin M, Ambesi-Impiombato A, Qin Y, Herranz D, Bansal M, Girardi T, Paietta E, Tallman MS, Rowe JM, De Keersmaecker K, Califano A, Ferrando AA. Sanchez-Martin M, et al. Among authors: girardi t. Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):2006-2011. doi: 10.1073/pnas.1611831114. Epub 2017 Feb 7. Proc Natl Acad Sci U S A. 2017. PMID: 28174276 Free PMC article.
T-ALL: ALL a matter of Translation?
Girardi T, De Keersmaecker K. Girardi T, et al. Haematologica. 2015 Mar;100(3):293-5. doi: 10.3324/haematol.2014.118562. Haematologica. 2015. PMID: 25740104 Free PMC article. No abstract available.
The genetics and molecular biology of T-ALL.
Girardi T, Vicente C, Cools J, De Keersmaecker K. Girardi T, et al. Blood. 2017 Mar 2;129(9):1113-1123. doi: 10.1182/blood-2016-10-706465. Epub 2017 Jan 23. Blood. 2017. PMID: 28115373 Free PMC article. Review.
The T-cell leukemia-associated ribosomal RPL10 R98S mutation enhances JAK-STAT signaling.
Girardi T, Vereecke S, Sulima SO, Khan Y, Fancello L, Briggs JW, Schwab C, de Beeck JO, Verbeeck J, Royaert J, Geerdens E, Vicente C, Bornschein S, Harrison CJ, Meijerink JP, Cools J, Dinman JD, Kampen KR, De Keersmaecker K. Girardi T, et al. Leukemia. 2018 Mar;32(3):809-819. doi: 10.1038/leu.2017.225. Epub 2017 Jul 24. Leukemia. 2018. PMID: 28744013 Free PMC article.
The ribosomal RPL10 R98S mutation drives IRES-dependent BCL-2 translation in T-ALL.
Kampen KR, Sulima SO, Verbelen B, Girardi T, Vereecke S, Rinaldi G, Verbeeck J, Op de Beeck J, Uyttebroeck A, Meijerink JPP, Moorman AV, Harrison CJ, Spincemaille P, Cools J, Cassiman D, Fendt SM, Vermeersch P, De Keersmaecker K. Kampen KR, et al. Among authors: girardi t. Leukemia. 2019 Feb;33(2):319-332. doi: 10.1038/s41375-018-0176-z. Epub 2018 Jun 21. Leukemia. 2019. PMID: 29930300 Free PMC article.
Translatome analysis reveals altered serine and glycine metabolism in T-cell acute lymphoblastic leukemia cells.
Kampen KR, Fancello L, Girardi T, Rinaldi G, Planque M, Sulima SO, Loayza-Puch F, Verbelen B, Vereecke S, Verbeeck J, Op de Beeck J, Royaert J, Vermeersch P, Cassiman D, Cools J, Agami R, Fiers M, Fendt SM, De Keersmaecker K. Kampen KR, et al. Among authors: girardi t. Nat Commun. 2019 Jun 11;10(1):2542. doi: 10.1038/s41467-019-10508-2. Nat Commun. 2019. PMID: 31186416 Free PMC article.
Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia.
De Keersmaecker K, Atak ZK, Li N, Vicente C, Patchett S, Girardi T, Gianfelici V, Geerdens E, Clappier E, Porcu M, Lahortiga I, Lucà R, Yan J, Hulselmans G, Vranckx H, Vandepoel R, Sweron B, Jacobs K, Mentens N, Wlodarska I, Cauwelier B, Cloos J, Soulier J, Uyttebroeck A, Bagni C, Hassan BA, Vandenberghe P, Johnson AW, Aerts S, Cools J. De Keersmaecker K, et al. Among authors: girardi t. Nat Genet. 2013 Feb;45(2):186-90. doi: 10.1038/ng.2508. Epub 2012 Dec 23. Nat Genet. 2013. PMID: 23263491 Free PMC article.
NUP214-ABL1-mediated cell proliferation in T-cell acute lymphoblastic leukemia is dependent on the LCK kinase and various interacting proteins.
De Keersmaecker K, Porcu M, Cox L, Girardi T, Vandepoel R, de Beeck JO, Gielen O, Mentens N, Bennett KL, Hantschel O. De Keersmaecker K, et al. Among authors: girardi t. Haematologica. 2014 Jan;99(1):85-93. doi: 10.3324/haematol.2013.088674. Epub 2013 Jul 19. Haematologica. 2014. PMID: 23872305 Free PMC article.
Correction: The ribosomal RPL10 R98S mutation drives IRES-dependent BCL-2 translation in T-ALL.
Kampen KR, Sulima SO, Verbelen B, Girardi T, Vereecke S, Fancello L, Rinaldi G, Verbeeck J, Op de Beeck J, Uyttebroeck A, Meijerink JPP, Moorman AV, Harrison CJ, Spincemaille P, Cools J, Cassiman D, Fendt SM, Vermeersch P, De Keersmaecker K. Kampen KR, et al. Among authors: girardi t. Leukemia. 2019 Apr;33(4):1055-1062. doi: 10.1038/s41375-019-0424-x. Leukemia. 2019. PMID: 30850735 Free PMC article.
Exploitation of the ribosomal protein L10 R98S mutation to enhance recombinant protein production in mammalian cells.
Verbelen B, Girardi T, Sulima SO, Vereecke S, Verstraete P, Verbeeck J, Royaert J, Cinque S, Montanaro L, Penzo M, Imbrechts M, Geukens N, Geuens T, Dierckx K, Pepe D, Kampen K, De Keersmaecker K. Verbelen B, et al. Among authors: girardi t. Eng Life Sci. 2022 Jan 14;22(2):100-114. doi: 10.1002/elsc.202100124. eCollection 2022 Feb. Eng Life Sci. 2022. PMID: 35140557 Free PMC article.
23 results