Lin H - Search Results

1

Mechanisms responsible for the synergistic antileukemic interactions between ATR inhibition and cytarabine in acute myeloid leukemia cells.

Ma J, Li X, Su Y, Zhao J, Luedtke DA, Epshteyn V, Edwards H, Wang G, Wang Z, Chu R, Taub JW, Lin H, Wang Y, Ge Y. Ma J, et al. Among authors: lin h. Sci Rep. 2017 Feb 8;7:41950. doi: 10.1038/srep41950. Sci Rep. 2017. PMID: 28176818 Free PMC article.

2

Cotargeting of Bcl-2 and Mcl-1 shows promising antileukemic activity against AML cells including those with acquired cytarabine resistance.

Liu F, Zhao Q, Su Y, Lv J, Gai Y, Liu S, Lin H, Wang Y, Wang G. Liu F, et al. Among authors: lin h. Exp Hematol. 2022 Jan;105:39-49. doi: 10.1016/j.exphem.2021.10.006. Epub 2021 Nov 9. Exp Hematol. 2022. PMID: 34767916 Free article.

3

Venetoclax enhances DNA damage induced by XPO1 inhibitors: A novel mechanism underlying the synergistic antileukaemic effect in acute myeloid leukaemia.

Yu H, Wu S, Liu S, Li X, Gai Y, Lin H, Wang Y, Edwards H, Ge Y, Wang G. Yu H, et al. Among authors: lin h. J Cell Mol Med. 2022 May;26(9):2646-2657. doi: 10.1111/jcmm.17274. Epub 2022 Mar 31. J Cell Mol Med. 2022. PMID: 35355406 Free PMC article.

4

CHK1 plays a critical role in the anti-leukemic activity of the wee1 inhibitor MK-1775 in acute myeloid leukemia cells.

Qi W, Xie C, Li C, Caldwell JT, Edwards H, Taub JW, Wang Y, Lin H, Ge Y. Qi W, et al. Among authors: lin h. J Hematol Oncol. 2014 Aug 1;7:53. doi: 10.1186/s13045-014-0053-9. J Hematol Oncol. 2014. PMID: 25084614 Free PMC article.

5

Synergistic anti-leukemic interactions between panobinostat and MK-1775 in acute myeloid leukemia ex vivo.

Qi W, Zhang W, Edwards H, Chu R, Madlambayan GJ, Taub JW, Wang Z, Wang Y, Li C, Lin H, Ge Y. Qi W, et al. Among authors: lin h. Cancer Biol Ther. 2015;16(12):1784-93. doi: 10.1080/15384047.2015.1095406. Cancer Biol Ther. 2015. PMID: 26529495 Free PMC article.

6

Binding of Released Bim to Mcl-1 is a Mechanism of Intrinsic Resistance to ABT-199 which can be Overcome by Combination with Daunorubicin or Cytarabine in AML Cells.

Niu X, Zhao J, Ma J, Xie C, Edwards H, Wang G, Caldwell JT, Xiang S, Zhang X, Chu R, Wang ZJ, Lin H, Taub JW, Ge Y. Niu X, et al. Among authors: lin h. Clin Cancer Res. 2016 Sep 1;22(17):4440-51. doi: 10.1158/1078-0432.CCR-15-3057. Epub 2016 Apr 21. Clin Cancer Res. 2016. PMID: 27103402 Free PMC article.

7

Inhibition of CHK1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells.

Zhao J, Niu X, Li X, Edwards H, Wang G, Wang Y, Taub JW, Lin H, Ge Y. Zhao J, et al. Among authors: lin h. Oncotarget. 2016 Jun 7;7(23):34785-99. doi: 10.18632/oncotarget.9185. Oncotarget. 2016. PMID: 27166183 Free PMC article.

8

Synthesis and Antileukemic Activities of Piperlongumine and HDAC Inhibitor Hybrids against Acute Myeloid Leukemia Cells.

Liao Y, Niu X, Chen B, Edwards H, Xu L, Xie C, Lin H, Polin L, Taub JW, Ge Y, Qin Z. Liao Y, et al. Among authors: lin h. J Med Chem. 2016 Sep 8;59(17):7974-90. doi: 10.1021/acs.jmedchem.6b00772. Epub 2016 Aug 24. J Med Chem. 2016. PMID: 27505848 Free PMC article.

9

Synergistic anti-leukemic interactions between ABT-199 and panobinostat in acute myeloid leukemia ex vivo.

Schwartz J, Niu X, Walton E, Hurley L, Lin H, Edwards H, Taub JW, Wang Z, Ge Y. Schwartz J, et al. Among authors: lin h. Am J Transl Res. 2016 Sep 15;8(9):3893-3902. eCollection 2016. Am J Transl Res. 2016. PMID: 27725868 Free PMC article.

10

Targeting PI3K, mTOR, ERK, and Bcl-2 signaling network shows superior antileukemic activity against AML ex vivo.

Su Y, Li X, Ma J, Zhao J, Liu S, Wang G, Edwards H, Taub JW, Lin H, Ge Y. Su Y, et al. Among authors: lin h. Biochem Pharmacol. 2018 Feb;148:13-26. doi: 10.1016/j.bcp.2017.11.022. Epub 2017 Dec 5. Biochem Pharmacol. 2018. PMID: 29208365 Free PMC article.

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