Stupack DG - Search Results

1

Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer.

Delaney JR, Patel CB, Willis KM, Haghighiabyaneh M, Axelrod J, Tancioni I, Lu D, Bapat J, Young S, Cadassou O, Bartakova A, Sheth P, Haft C, Hui S, Saenz C, Schlaepfer DD, Harismendy O, Stupack DG. Delaney JR, et al. Among authors: stupack dg. Nat Commun. 2017 Feb 15;8:14423. doi: 10.1038/ncomms14423. Nat Commun. 2017. PMID: 28198375 Free PMC article.

2

Association of p130CAS with phosphatidylinositol-3-OH kinase mediates adenovirus cell entry.

Li E, Stupack DG, Brown SL, Klemke R, Schlaepfer DD, Nemerow GR. Li E, et al. Among authors: stupack dg. J Biol Chem. 2000 May 12;275(19):14729-35. doi: 10.1074/jbc.275.19.14729. J Biol Chem. 2000. PMID: 10799562 Free article.

3

Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling.

Eliceiri BP, Puente XS, Hood JD, Stupack DG, Schlaepfer DD, Huang XZ, Sheppard D, Cheresh DA. Eliceiri BP, et al. Among authors: stupack dg. J Cell Biol. 2002 Apr 1;157(1):149-60. doi: 10.1083/jcb.200109079. Epub 2002 Apr 1. J Cell Biol. 2002. PMID: 11927607 Free PMC article.

4

Potentiation of neuroblastoma metastasis by loss of caspase-8.

Stupack DG, Teitz T, Potter MD, Mikolon D, Houghton PJ, Kidd VJ, Lahti JM, Cheresh DA. Stupack DG, et al. Nature. 2006 Jan 5;439(7072):95-9. doi: 10.1038/nature04323. Nature. 2006. PMID: 16397500

5

Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors.

Mitra SK, Mikolon D, Molina JE, Hsia DA, Hanson DA, Chi A, Lim ST, Bernard-Trifilo JA, Ilic D, Stupack DG, Cheresh DA, Schlaepfer DD. Mitra SK, et al. Among authors: stupack dg. Oncogene. 2006 Sep 28;25(44):5969-84. doi: 10.1038/sj.onc.1209588. Epub 2006 May 8. Oncogene. 2006. PMID: 16682956

6

Distinct FAK-Src activation events promote alpha5beta1 and alpha4beta1 integrin-stimulated neuroblastoma cell motility.

Wu L, Bernard-Trifilo JA, Lim Y, Lim ST, Mitra SK, Uryu S, Chen M, Pallen CJ, Cheung NK, Mikolon D, Mielgo A, Stupack DG, Schlaepfer DD. Wu L, et al. Among authors: stupack dg. Oncogene. 2008 Feb 28;27(10):1439-48. doi: 10.1038/sj.onc.1210770. Epub 2007 Sep 10. Oncogene. 2008. PMID: 17828307 Free PMC article.

7

FERM control of FAK function: implications for cancer therapy.

Lim ST, Mikolon D, Stupack DG, Schlaepfer DD. Lim ST, et al. Among authors: stupack dg. Cell Cycle. 2008 Aug;7(15):2306-14. doi: 10.4161/cc.6367. Epub 2008 May 29. Cell Cycle. 2008. PMID: 18677107 Free PMC article. Review.

8

Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis.

Barbero S, Mielgo A, Torres V, Teitz T, Shields DJ, Mikolon D, Bogyo M, Barilà D, Lahti JM, Schlaepfer D, Stupack DG. Barbero S, et al. Among authors: stupack dg. Cancer Res. 2009 May 1;69(9):3755-63. doi: 10.1158/0008-5472.CAN-08-3937. Epub 2009 Apr 21. Cancer Res. 2009. PMID: 19383910 Free PMC article.

9

PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments.

Tanjoni I, Walsh C, Uryu S, Tomar A, Nam JO, Mielgo A, Lim ST, Liang C, Koenig M, Sun C, Patel N, Kwok C, McMahon G, Stupack DG, Schlaepfer DD. Tanjoni I, et al. Among authors: stupack dg. Cancer Biol Ther. 2010 May 15;9(10):764-77. doi: 10.4161/cbt.9.10.11434. Cancer Biol Ther. 2010. PMID: 20234191 Free PMC article.

10

Oral delivery of PND-1186 FAK inhibitor decreases tumor growth and spontaneous breast to lung metastasis in pre-clinical models.

Walsh C, Tanjoni I, Uryu S, Tomar A, Nam JO, Luo H, Phillips A, Patel N, Kwok C, McMahon G, Stupack DG, Schlaepfer DD. Walsh C, et al. Among authors: stupack dg. Cancer Biol Ther. 2010 May 15;9(10):778-90. doi: 10.4161/cbt.9.10.11433. Cancer Biol Ther. 2010. PMID: 20234193 Free PMC article.

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