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Page 1
Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer.
Delaney JR, Patel CB, Willis KM, Haghighiabyaneh M, Axelrod J, Tancioni I, Lu D, Bapat J, Young S, Cadassou O, Bartakova A, Sheth P, Haft C, Hui S, Saenz C, Schlaepfer DD, Harismendy O, Stupack DG. Delaney JR, et al. Among authors: tancioni i. Nat Commun. 2017 Feb 15;8:14423. doi: 10.1038/ncomms14423. Nat Commun. 2017. PMID: 28198375 Free PMC article.
A strategy to combine pathway-targeted low toxicity drugs in ovarian cancer.
Delaney JR, Patel C, McCabe KE, Lu D, Davis MA, Tancioni I, von Schalscha T, Bartakova A, Haft C, Schlaepfer DD, Stupack DG. Delaney JR, et al. Among authors: tancioni i. Oncotarget. 2015 Oct 13;6(31):31104-18. doi: 10.18632/oncotarget.5093. Oncotarget. 2015. PMID: 26418751 Free PMC article.
Autophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors.
Delaney JR, Patel CB, Bapat J, Jones CM, Ramos-Zapatero M, Ortell KK, Tanios R, Haghighiabyaneh M, Axelrod J, DeStefano JW, Tancioni I, Schlaepfer DD, Harismendy O, La Spada AR, Stupack DG. Delaney JR, et al. Among authors: tancioni i. PLoS Genet. 2020 Jan 10;16(1):e1008558. doi: 10.1371/journal.pgen.1008558. eCollection 2020 Jan. PLoS Genet. 2020. PMID: 31923184 Free PMC article.
Rgnef promotes ovarian tumor progression and confers protection from oxidative stress.
Kleinschmidt EG, Miller NLG, Ozmadenci D, Tancioni I, Osterman CD, Barrie AM, Taylor KN, Ye A, Jiang S, Connolly DC, Stupack DG, Schlaepfer DD. Kleinschmidt EG, et al. Among authors: tancioni i. Oncogene. 2019 Sep;38(36):6323-6337. doi: 10.1038/s41388-019-0881-8. Epub 2019 Jul 15. Oncogene. 2019. PMID: 31308489 Free PMC article.
FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy.
Diaz Osterman CJ, Ozmadenci D, Kleinschmidt EG, Taylor KN, Barrie AM, Jiang S, Bean LM, Sulzmaier FJ, Jean C, Tancioni I, Anderson K, Uryu S, Cordasco EA, Li J, Chen XL, Fu G, Ojalill M, Rappu P, Heino J, Mark AM, Xu G, Fisch KM, Kolev VN, Weaver DT, Pachter JA, Győrffy B, McHale MT, Connolly DC, Molinolo A, Stupack DG, Schlaepfer DD. Diaz Osterman CJ, et al. Among authors: tancioni i. Elife. 2019 Sep 3;8:e47327. doi: 10.7554/eLife.47327. Elife. 2019. PMID: 31478830 Free PMC article.
13 results