Yan GY - Search Results

1

Synthesis, biological evaluation and molecular docking study of N-(2-methoxyphenyl)-6-((4-nitrophenyl)sulfonyl)benzamide derivatives as potent HIV-1 Vif antagonists.

Zhou M, Luo RH, Hou XY, Wang RR, Yan GY, Chen H, Zhang RH, Shi JY, Zheng YT, Li R, Wei YQ. Zhou M, et al. Among authors: yan gy. Eur J Med Chem. 2017 Mar 31;129:310-324. doi: 10.1016/j.ejmech.2017.01.010. Epub 2017 Jan 12. Eur J Med Chem. 2017. PMID: 28235704

2

Analysis of furo[3,2-c]tetrahydroquinoline and pyrano[3,2-c]tetrahydroquinoline derivatives as antitumor agents and their metabolites by liquid chromatography/electrospray ionization tandem mass spectrometry.

Hou X, Luo H, Zhong H, Wu F, Zhou M, Zhang W, Han X, Yan G, Zhang M, Lu L, Ding Z, He G, Li R. Hou X, et al. Rapid Commun Mass Spectrom. 2013 Jun 15;27(11):1222-30. doi: 10.1002/rcm.6562. Rapid Commun Mass Spectrom. 2013. PMID: 23650035

3

Synthesis and biological evaluation of 4-(1,2,3-triazol-1-yl)coumarin derivatives as potential antitumor agents.

Zhang W, Li Z, Zhou M, Wu F, Hou X, Luo H, Liu H, Han X, Yan G, Ding Z, Li R. Zhang W, et al. Bioorg Med Chem Lett. 2014 Feb 1;24(3):799-807. doi: 10.1016/j.bmcl.2013.12.095. Epub 2013 Dec 29. Bioorg Med Chem Lett. 2014. PMID: 24418772

4

Synthesis and biological evaluation of novel 2,3-dihydrochromeno[3,4-d]imidazol-4(1H)-one derivatives as potent anticancer cell proliferation and migration agents.

Han X, Luo J, Wu F, Hou X, Yan G, Zhou M, Zhang M, Pu C, Li R. Han X, et al. Eur J Med Chem. 2016 May 23;114:232-43. doi: 10.1016/j.ejmech.2016.01.035. Epub 2016 Feb 5. Eur J Med Chem. 2016. PMID: 26994691

5

Design, Synthesis, and Biological Evaluation of Dimorpholine Substituted Thienopyrimidines as Potential Class I PI3K/mTOR Dual Inhibitors.

Zhan M, Deng Y, Zhao L, Yan G, Wang F, Tian Y, Zhang L, Jiang H, Chen Y. Zhan M, et al. J Med Chem. 2017 May 11;60(9):4023-4035. doi: 10.1021/acs.jmedchem.7b00357. Epub 2017 Apr 24. J Med Chem. 2017. PMID: 28409639

6

Design, synthesis and biological evaluation of indole derivatives as Vif inhibitors.

Pu C, Luo RH, Zhang M, Hou X, Yan G, Luo J, Zheng YT, Li R. Pu C, et al. Bioorg Med Chem Lett. 2017 Sep 1;27(17):4150-4155. doi: 10.1016/j.bmcl.2017.07.026. Epub 2017 Jul 10. Bioorg Med Chem Lett. 2017. PMID: 28754362

7

Pharmacophore-based virtual screening, molecular docking, molecular dynamics simulation, and biological evaluation for the discovery of novel BRD4 inhibitors.

Yan G, Hou M, Luo J, Pu C, Hou X, Lan S, Li R. Yan G, et al. Chem Biol Drug Des. 2018 Feb;91(2):478-490. doi: 10.1111/cbdd.13109. Epub 2017 Oct 9. Chem Biol Drug Des. 2018. PMID: 28901664

8

Assessing the performance of docking scoring function, FEP, MM-GBSA, and QM/MM-GBSA approaches on a series of PLK1 inhibitors.

Pu C, Yan G, Shi J, Li R. Pu C, et al. Medchemcomm. 2017 May 22;8(7):1452-1458. doi: 10.1039/c7md00184c. eCollection 2017 Jul 1. Medchemcomm. 2017. PMID: 30108856 Free PMC article.

9

Synthesis and biological evaluation of 3-(1,3,4-oxadiazol-2-yl)-1,8-naphthyridin-4(1H)-ones as cisplatin sensitizers.

Hou X, Luo H, Zhang M, Yan G, Pu C, Lan S, Li R. Hou X, et al. Medchemcomm. 2018 Sep 25;9(11):1949-1960. doi: 10.1039/c8md00464a. eCollection 2018 Nov 1. Medchemcomm. 2018. PMID: 30568762 Free PMC article.

10

Discovery and biological evaluation of novel androgen receptor antagonist for castration-resistant prostate cancer.

Yu J, Zhang L, Yan G, Zhou P, Cao C, Zhou F, Li X, Chen Y. Yu J, et al. Eur J Med Chem. 2019 Jun 1;171:265-281. doi: 10.1016/j.ejmech.2019.03.041. Epub 2019 Mar 22. Eur J Med Chem. 2019. PMID: 30925341

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