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Page 1
Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation.
Cohen ES, Scott IC, Majithiya JB, Rapley L, Kemp BP, England E, Rees DG, Overed-Sayer CL, Woods J, Bond NJ, Veyssier CS, Embrey KJ, Sims DA, Snaith MR, Vousden KA, Strain MD, Chan DT, Carmen S, Huntington CE, Flavell L, Xu J, Popovic B, Brightling CE, Vaughan TJ, Butler R, Lowe DC, Higazi DR, Corkill DJ, May RD, Sleeman MA, Mustelin T. Cohen ES, et al. Among authors: bond nj. Nat Commun. 2015 Sep 14;6:8327. doi: 10.1038/ncomms9327. Nat Commun. 2015. PMID: 26365875 Free PMC article.
The TGF-β inhibitory activity of antibody 37E1B5 depends on its H-CDR2 glycan.
Tsui P, Higazi DR, Wu Y, Dunmore R, Solier E, Kasali T, Bond NJ, Huntington C, Carruthers A, Hood J, Borrok MJ, Barnes A, Rickert K, Phipps S, Shirinian L, Zhu J, Bowen MA, Dall'Acqua W, Murray LA. Tsui P, et al. Among authors: bond nj. MAbs. 2017 Jan;9(1):104-113. doi: 10.1080/19420862.2016.1255390. Epub 2016 Nov 11. MAbs. 2017. PMID: 27834568 Free PMC article.
Engineering of a GLP-1 analogue peptide/anti-PCSK9 antibody fusion for type 2 diabetes treatment.
Chodorge M, Celeste AJ, Grimsby J, Konkar A, Davidsson P, Fairman D, Jenkinson L, Naylor J, White N, Seaman JC, Dickson K, Kemp B, Spooner J, Rossy E, Hornigold DC, Trevaskis JL, Bond NJ, London TB, Buchanan A, Vaughan T, Rondinone CM, Osbourn JK. Chodorge M, et al. Among authors: bond nj. Sci Rep. 2018 Dec 3;8(1):17545. doi: 10.1038/s41598-018-35869-4. Sci Rep. 2018. PMID: 30510163 Free PMC article.
Interconversion of Unexpected Thiol States Affects the Stability, Structure, and Dynamics of Antibody Engineered for Site-Specific Conjugation.
Orozco CT, Edgeworth MJ, Devine PWA, Hines AR, Cornwell O, Thompson C, Wang X, Phillips JJ, Ravn P, Jackson SE, Bond NJ. Orozco CT, et al. Among authors: bond nj. Bioconjug Chem. 2021 Aug 18;32(8):1834-1844. doi: 10.1021/acs.bioconjchem.1c00286. Epub 2021 Aug 9. Bioconjug Chem. 2021. PMID: 34369158 Free article.
An in vivo platform to select and evolve aggregation-resistant proteins.
Ebo JS, Saunders JC, Devine PWA, Gordon AM, Warwick AS, Schiffrin B, Chin SE, England E, Button JD, Lloyd C, Bond NJ, Ashcroft AE, Radford SE, Lowe DC, Brockwell DJ. Ebo JS, et al. Among authors: bond nj. Nat Commun. 2020 Apr 14;11(1):1816. doi: 10.1038/s41467-020-15667-1. Nat Commun. 2020. PMID: 32286330 Free PMC article.
34 results