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Protective effect of human leukocyte antigen B27 in hepatitis C virus infection requires the presence of a genotype-specific immunodominant CD8+ T-cell epitope.
Neumann-Haefelin C, Timm J, Schmidt J, Kersting N, Fitzmaurice K, Oniangue-Ndza C, Kemper MN, Humphreys I, McKiernan S, Kelleher D, Lohmann V, Bowness P, Huzly D, Rosen HR, Kim AY, Lauer GM, Allen TM, Barnes E, Roggendorf M, Blum HE, Thimme R. Neumann-Haefelin C, et al. Among authors: timm j. Hepatology. 2010 Jan;51(1):54-62. doi: 10.1002/hep.23275. Hepatology. 2010. PMID: 20034048 Free PMC article.
CD8+ T-cell response promotes evolution of hepatitis C virus nonstructural proteins.
Ruhl M, Knuschke T, Schewior K, Glavinic L, Neumann-Haefelin C, Chang DI, Klein M, Heinemann FM, Tenckhoff H, Wiese M, Horn PA, Viazov S, Spengler U, Roggendorf M, Scherbaum N, Nattermann J, Hoffmann D, Timm J; East German HCV Study Group. Ruhl M, et al. Among authors: timm j. Gastroenterology. 2011 Jun;140(7):2064-73. doi: 10.1053/j.gastro.2011.02.060. Epub 2011 Mar 2. Gastroenterology. 2011. PMID: 21376049
The predictive value of IL28B gene polymorphism for spontaneous clearance in a single source outbreak cohort is limited in patients carrying the CCR5Δ32 mutation.
Nattermann J, Timm J, Nischalke HD, Olbrich A, Michalk M, Tillmann HL, Berg T, Wedemeyer H, Tenckhoff H, Wiese M, Kullig U, Göbel U, Capka E, Schiefke I, Güthof W, Grüngreiff K, König I, Roggendorf M, Sauerbruch T, Spengler U; East German HCV Study Group. Nattermann J, et al. Among authors: timm j. J Hepatol. 2011 Dec;55(6):1201-6. doi: 10.1016/j.jhep.2011.03.011. Epub 2011 Apr 13. J Hepatol. 2011. PMID: 21703201
HLA-B*27 subtype specificity determines targeting and viral evolution of a hepatitis C virus-specific CD8+ T cell epitope.
Nitschke K, Barriga A, Schmidt J, Timm J, Viazov S, Kuntzen T, Kim AY, Lauer GM, Allen TM, Gaudieri S, Rauch A, Lange CM, Sarrazin C, Eiermann T, Sidney J, Sette A, Thimme R, López D, Neumann-Haefelin C. Nitschke K, et al. Among authors: timm j. J Hepatol. 2014 Jan;60(1):22-9. doi: 10.1016/j.jhep.2013.08.009. Epub 2013 Aug 23. J Hepatol. 2014. PMID: 23978718 Free PMC article.
Hepatitis E Virus Infection as a Possible Cause of Acute Liver Failure in Europe.
Manka P, Bechmann LP, Coombes JD, Thodou V, Schlattjan M, Kahraman A, Syn WK, Saner F, Gerken G, Baba H, Verheyen J, Timm J, Canbay A. Manka P, et al. Among authors: timm j. Clin Gastroenterol Hepatol. 2015 Oct;13(10):1836-1842.e2; quiz e157-8. doi: 10.1016/j.cgh.2015.04.014. Epub 2015 Apr 23. Clin Gastroenterol Hepatol. 2015. PMID: 25912835
359 results