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Page 1
Muramyl Dipeptide-Based Postbiotics Mitigate Obesity-Induced Insulin Resistance via IRF4.
Cavallari JF, Fullerton MD, Duggan BM, Foley KP, Denou E, Smith BK, Desjardins EM, Henriksbo BD, Kim KJ, Tuinema BR, Stearns JC, Prescott D, Rosenstiel P, Coombes BK, Steinberg GR, Schertzer JD. Cavallari JF, et al. Among authors: schertzer jd. Cell Metab. 2017 May 2;25(5):1063-1074.e3. doi: 10.1016/j.cmet.2017.03.021. Epub 2017 Apr 20. Cell Metab. 2017. PMID: 28434881 Free article.
Whole body deletion of AMP-activated protein kinase {beta}2 reduces muscle AMPK activity and exercise capacity.
Steinberg GR, O'Neill HM, Dzamko NL, Galic S, Naim T, Koopman R, Jørgensen SB, Honeyman J, Hewitt K, Chen ZP, Schertzer JD, Scott JW, Koentgen F, Lynch GS, Watt MJ, van Denderen BJ, Campbell DJ, Kemp BE. Steinberg GR, et al. Among authors: schertzer jd. J Biol Chem. 2010 Nov 26;285(48):37198-209. doi: 10.1074/jbc.M110.102434. Epub 2010 Sep 20. J Biol Chem. 2010. PMID: 20855892 Free PMC article.
NOD1 activators link innate immunity to insulin resistance.
Schertzer JD, Tamrakar AK, Magalhães JG, Pereira S, Bilan PJ, Fullerton MD, Liu Z, Steinberg GR, Giacca A, Philpott DJ, Klip A. Schertzer JD, et al. Diabetes. 2011 Sep;60(9):2206-15. doi: 10.2337/db11-0004. Epub 2011 Jun 29. Diabetes. 2011. PMID: 21715553 Free PMC article.
AMP-activated protein kinase (AMPK) beta1beta2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise.
O'Neill HM, Maarbjerg SJ, Crane JD, Jeppesen J, Jørgensen SB, Schertzer JD, Shyroka O, Kiens B, van Denderen BJ, Tarnopolsky MA, Kemp BE, Richter EA, Steinberg GR. O'Neill HM, et al. Among authors: schertzer jd. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16092-7. doi: 10.1073/pnas.1105062108. Epub 2011 Sep 6. Proc Natl Acad Sci U S A. 2011. PMID: 21896769 Free PMC article.
Immunometabolism of AMPK in insulin resistance and atherosclerosis.
Fullerton MD, Steinberg GR, Schertzer JD. Fullerton MD, et al. Among authors: schertzer jd. Mol Cell Endocrinol. 2013 Feb 25;366(2):224-34. doi: 10.1016/j.mce.2012.02.004. Epub 2012 Feb 14. Mol Cell Endocrinol. 2013. PMID: 22361321 Review.
The ancient drug salicylate directly activates AMP-activated protein kinase.
Hawley SA, Fullerton MD, Ross FA, Schertzer JD, Chevtzoff C, Walker KJ, Peggie MW, Zibrova D, Green KA, Mustard KJ, Kemp BE, Sakamoto K, Steinberg GR, Hardie DG. Hawley SA, et al. Among authors: schertzer jd. Science. 2012 May 18;336(6083):918-22. doi: 10.1126/science.1215327. Epub 2012 Apr 19. Science. 2012. PMID: 22517326 Free PMC article.
Deletion of skeletal muscle SOCS3 prevents insulin resistance in obesity.
Jorgensen SB, O'Neill HM, Sylow L, Honeyman J, Hewitt KA, Palanivel R, Fullerton MD, Öberg L, Balendran A, Galic S, van der Poel C, Trounce IA, Lynch GS, Schertzer JD, Steinberg GR. Jorgensen SB, et al. Among authors: schertzer jd. Diabetes. 2013 Jan;62(1):56-64. doi: 10.2337/db12-0443. Epub 2012 Sep 6. Diabetes. 2013. PMID: 22961088 Free PMC article.
IL-6 is not essential for exercise-induced increases in glucose uptake.
O'Neill HM, Palanivel R, Wright DC, MacDonald T, Lally JS, Schertzer JD, Steinberg GR. O'Neill HM, et al. Among authors: schertzer jd. J Appl Physiol (1985). 2013 May;114(9):1151-7. doi: 10.1152/japplphysiol.00946.2012. Epub 2013 Feb 28. J Appl Physiol (1985). 2013. PMID: 23449935 Free article.
141 results