McCormack W - Search Results

1

Identification of a TLR2-regulated gene signature associated with tumor cell growth in gastric cancer.

West AC, Tang K, Tye H, Yu L, Deng N, Najdovska M, Lin SJ, Balic JJ, Okochi-Takada E, McGuirk P, Keogh B, McCormack W, Bhathal PS, Reilly M, Oshima M, Ushijima T, Tan P, Jenkins BJ. West AC, et al. Among authors: mccormack w. Oncogene. 2017 Sep 7;36(36):5134-5144. doi: 10.1038/onc.2017.121. Epub 2017 May 8. Oncogene. 2017. PMID: 28481875

2

STAT3-driven upregulation of TLR2 promotes gastric tumorigenesis independent of tumor inflammation.

Tye H, Kennedy CL, Najdovska M, McLeod L, McCormack W, Hughes N, Dev A, Sievert W, Ooi CH, Ishikawa TO, Oshima H, Bhathal PS, Parker AE, Oshima M, Tan P, Jenkins BJ. Tye H, et al. Among authors: mccormack w. Cancer Cell. 2012 Oct 16;22(4):466-78. doi: 10.1016/j.ccr.2012.08.010. Cancer Cell. 2012. PMID: 23079657 Free article.

3

Toll-like receptor 2: therapeutic target for gastric carcinogenesis.

McCormack W, Oshima M, Tan P, Jenkins B. McCormack W, et al. Oncotarget. 2012 Nov;3(11):1260-1. doi: 10.18632/oncotarget.735. Oncotarget. 2012. PMID: 23175464 Free PMC article. No abstract available.

4

Inhibiting TLR2 activation attenuates amyloid accumulation and glial activation in a mouse model of Alzheimer's disease.

McDonald CL, Hennessy E, Rubio-Araiz A, Keogh B, McCormack W, McGuirk P, Reilly M, Lynch MA. McDonald CL, et al. Among authors: mccormack w. Brain Behav Immun. 2016 Nov;58:191-200. doi: 10.1016/j.bbi.2016.07.143. Epub 2016 Jul 12. Brain Behav Immun. 2016. PMID: 27422717

5

Randomized, double-blind, placebo-controlled, dose-escalating phase I, healthy subjects study of intravenous OPN-305, a humanized anti-TLR2 antibody.

Reilly M, Miller RM, Thomson MH, Patris V, Ryle P, McLoughlin L, Mutch P, Gilboy P, Miller C, Broekema M, Keogh B, McCormack W, van de Wetering de Rooij J. Reilly M, et al. Among authors: mccormack w. Clin Pharmacol Ther. 2013 Nov;94(5):593-600. doi: 10.1038/clpt.2013.150. Epub 2013 Jul 23. Clin Pharmacol Ther. 2013. PMID: 23880971 Free PMC article. Clinical Trial.

6

Inhibition of TLR2 promotes graft function in a murine model of renal transplant ischemia-reperfusion injury.

Farrar CA, Keogh B, McCormack W, O'Shaughnessy A, Parker A, Reilly M, Sacks SH. Farrar CA, et al. Among authors: mccormack w. FASEB J. 2012 Feb;26(2):799-807. doi: 10.1096/fj.11-195396. Epub 2011 Oct 31. FASEB J. 2012. PMID: 22042224

7

Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures.

Ultaigh SN, Saber TP, McCormick J, Connolly M, Dellacasagrande J, Keogh B, McCormack W, Reilly M, O'Neill LA, McGuirk P, Fearon U, Veale DJ. Ultaigh SN, et al. Among authors: mccormack w. Arthritis Res Ther. 2011 Feb 23;13(1):R33. doi: 10.1186/ar3261. Arthritis Res Ther. 2011. PMID: 21345222 Free PMC article.

8

Treatment with OPN-305, a humanized anti-Toll-Like receptor-2 antibody, reduces myocardial ischemia/reperfusion injury in pigs.

Arslan F, Houtgraaf JH, Keogh B, Kazemi K, de Jong R, McCormack WJ, O'Neill LA, McGuirk P, Timmers L, Smeets MB, Akeroyd L, Reilly M, Pasterkamp G, de Kleijn DP. Arslan F, et al. Circ Cardiovasc Interv. 2012 Apr;5(2):279-87. doi: 10.1161/CIRCINTERVENTIONS.111.967596. Epub 2012 Feb 21. Circ Cardiovasc Interv. 2012. PMID: 22354933

9

Toll-like receptors and NOD-like receptors in rheumatic diseases.

McCormack WJ, Parker AE, O'Neill LA. McCormack WJ, et al. Arthritis Res Ther. 2009;11(5):243. doi: 10.1186/ar2729. Epub 2009 Oct 14. Arthritis Res Ther. 2009. PMID: 19835640 Free PMC article. Review.

10

Pigment epithelium-derived factor (PEDF) interacts with transportin SR2, and active nuclear import is facilitated by a novel nuclear localization motif.

Anguissola S, McCormack WJ, Morrin MA, Higgins WJ, Fox DM, Worrall DM. Anguissola S, et al. PLoS One. 2011;6(10):e26234. doi: 10.1371/journal.pone.0026234. Epub 2011 Oct 18. PLoS One. 2011. PMID: 22028839 Free PMC article.

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