Thorpe LM - Search Results

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PI3K-p110α mediates the oncogenic activity induced by loss of the novel tumor suppressor PI3K-p85α.

Thorpe LM, Spangle JM, Ohlson CE, Cheng H, Roberts TM, Cantley LC, Zhao JJ. Thorpe LM, et al. Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7095-7100. doi: 10.1073/pnas.1704706114. Epub 2017 Jun 19. Proc Natl Acad Sci U S A. 2017. PMID: 28630349 Free PMC article.

PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting.

Thorpe LM, Yuzugullu H, Zhao JJ. Thorpe LM, et al. Nat Rev Cancer. 2015 Jan;15(1):7-24. doi: 10.1038/nrc3860. Nat Rev Cancer. 2015. PMID: 25533673 Free PMC article. Review.

NTRK2 activation cooperates with PTEN deficiency in T-ALL through activation of both the PI3K-AKT and JAK-STAT3 pathways.

Yuzugullu H, Von T, Thorpe LM, Walker SR, Roberts TM, Frank DA, Zhao JJ. Yuzugullu H, et al. Among authors: thorpe lm. Cell Discov. 2016 Sep 20;2:16030. doi: 10.1038/celldisc.2016.30. eCollection 2016. Cell Discov. 2016. PMID: 27672444 Free PMC article.

Significant and durable clinical benefit from trastuzumab in 2 patients with HER2-amplified salivary gland cancer and a review of the literature.

Thorpe LM, Schrock AB, Erlich RL, Miller VA, Knost J, Le-Lindqwister N, Jujjavarapu S, Ali SM, Liu JJ. Thorpe LM, et al. Head Neck. 2017 Mar;39(3):E40-E44. doi: 10.1002/hed.24634. Epub 2016 Dec 22. Head Neck. 2017. PMID: 28006087 Review.

Apical constriction and invagination downstream of the canonical Wnt signaling pathway require Rho1 and Myosin II.

Zimmerman SG, Thorpe LM, Medrano VR, Mallozzi CA, McCartney BM. Zimmerman SG, et al. Among authors: thorpe lm. Dev Biol. 2010 Apr 1;340(1):54-66. doi: 10.1016/j.ydbio.2010.01.021. Epub 2010 Jan 25. Dev Biol. 2010. PMID: 20102708 Free PMC article.

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