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Arsenic Compromises Both p97 and Proteasome Functions.
Tillotson J, Zerio CJ, Harder B, Ambrose AJ, Jung KS, Kang M, Zhang DD, Chapman E. Tillotson J, et al. Among authors: kang m. Chem Res Toxicol. 2017 Jul 17;30(7):1508-1514. doi: 10.1021/acs.chemrestox.7b00158. Epub 2017 Jul 7. Chem Res Toxicol. 2017. PMID: 28636814 Free PMC article.
Selective inhibition of p97 by chlorinated analogues of dehydrocurvularin.
Tillotson J, Bashyal BP, Kang M, Shi T, De La Cruz F, Gunatilaka AA, Chapman E. Tillotson J, et al. Among authors: kang m. Org Biomol Chem. 2016 Jul 7;14(25):5918-21. doi: 10.1039/c6ob00560h. Epub 2016 May 25. Org Biomol Chem. 2016. PMID: 27223265 Free PMC article.
Withaferin A Analogs That Target the AAA+ Chaperone p97.
Tao S, Tillotson J, Wijeratne EMK, Xu YM, Kang M, Wu T, Lau EC, Mesa C, Mason DJ, Brown RV, Clair JJ, Gunatilaka AAL, Zhang DD, Chapman E. Tao S, et al. Among authors: kang m. ACS Chem Biol. 2015 Aug 21;10(8):1916-1924. doi: 10.1021/acschembio.5b00367. Epub 2015 Jun 3. ACS Chem Biol. 2015. PMID: 26006219 Free PMC article.
An Isoform-Selective PTP1B Inhibitor Derived from Nitrogen-Atom Augmentation of Radicicol.
Shi T, Wijeratne EMK, Solano C, Ambrose AJ, Ross AB, Norwood C, Orido CK, Grigoryan T, Tillotson J, Kang M, Luo G, Keegan BM, Hu W, Blagg BSJ, Zhang DD, Gunatilaka AAL, Chapman E. Shi T, et al. Among authors: kang m. Biochemistry. 2019 Jul 30;58(30):3225-3231. doi: 10.1021/acs.biochem.9b00499. Epub 2019 Jul 18. Biochemistry. 2019. PMID: 31298844 Free PMC article.
The complexities of p97 function in health and disease.
Chapman E, Fry AN, Kang M. Chapman E, et al. Among authors: kang m. Mol Biosyst. 2011 Mar;7(3):700-10. doi: 10.1039/c0mb00176g. Epub 2010 Dec 14. Mol Biosyst. 2011. PMID: 21152665 Free PMC article. Review.
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