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Preclinical studies using cisplatin/carboplatin to restore the Enzalutamide sensitivity via degrading the androgen receptor splicing variant 7 (ARv7) to further suppress Enzalutamide resistant prostate cancer.
Chou FJ, Lin C, Tian H, Lin W, You B, Lu J, Sahasrabudhe D, Huang CP, Yang V, Yeh S, Niu Y, Chang C. Chou FJ, et al. Among authors: lin c, lin w. Cell Death Dis. 2020 Nov 2;11(11):942. doi: 10.1038/s41419-020-02970-4. Cell Death Dis. 2020. PMID: 33139720 Free PMC article.
Preclinical studies show using enzalutamide is less effective in docetaxel-pretreated than in docetaxel-naïve prostate cancer cells.
Lin C, Chou FJ, Lu J, Lin W, Truong M, Tian H, Sun Y, Luo J, Yang R, Niu Y, Nadal R, Antonarakis ES, Cordon-Cardo C, Sahasrabudhe D, Huang CP, Yeh S, Li G, Chang C. Lin C, et al. Among authors: lin w. Aging (Albany NY). 2020 Sep 10;12(17):17694-17712. doi: 10.18632/aging.103917. Epub 2020 Sep 10. Aging (Albany NY). 2020. PMID: 32920545 Free PMC article.
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