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Plk1 regulates contraction of postmitotic smooth muscle cells and is required for vascular homeostasis.
de Cárcer G, Wachowicz P, Martínez-Martínez S, Oller J, Méndez-Barbero N, Escobar B, González-Loyola A, Takaki T, El Bakkali A, Cámara JA, Jiménez-Borreguero LJ, Bustelo XR, Cañamero M, Mulero F, de Los Ángeles Sevilla M, Montero MJ, Redondo JM, Malumbres M. de Cárcer G, et al. Among authors: de los angeles sevilla m. Nat Med. 2017 Aug;23(8):964-974. doi: 10.1038/nm.4364. Epub 2017 Jul 10. Nat Med. 2017. PMID: 28692064
Heterozygous disruption of activin receptor-like kinase 1 is associated with increased arterial pressure in mice.
González-Núñez M, Riolobos AS, Castellano O, Fuentes-Calvo I, de los Ángeles Sevilla M, Oujo B, Pericacho M, Cruz-Gonzalez I, Pérez-Barriocanal F, ten Dijke P, López-Novoa JM. González-Núñez M, et al. Among authors: de los angeles sevilla m. Dis Model Mech. 2015 Nov;8(11):1427-39. doi: 10.1242/dmm.019695. Epub 2015 Sep 17. Dis Model Mech. 2015. PMID: 26398936 Free PMC article.