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A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma.
O'Rourke DM, Nasrallah MP, Desai A, Melenhorst JJ, Mansfield K, Morrissette JJD, Martinez-Lage M, Brem S, Maloney E, Shen A, Isaacs R, Mohan S, Plesa G, Lacey SF, Navenot JM, Zheng Z, Levine BL, Okada H, June CH, Brogdon JL, Maus MV. O'Rourke DM, et al. Among authors: maus mv. Sci Transl Med. 2017 Jul 19;9(399):eaaa0984. doi: 10.1126/scitranslmed.aaa0984. Sci Transl Med. 2017. PMID: 28724573 Free PMC article. Clinical Trial.
Zoom Zoom: racing CARs for multiple myeloma.
Maus MV, June CH. Maus MV, et al. Clin Cancer Res. 2013 Apr 15;19(8):1917-9. doi: 10.1158/1078-0432.CCR-13-0168. Epub 2013 Feb 26. Clin Cancer Res. 2013. PMID: 23444214 Free PMC article.
187 results