Abu-Amer Y - Search Results

1

Bone matrix components activate the NLRP3 inflammasome and promote osteoclast differentiation.

Alippe Y, Wang C, Ricci B, Xiao J, Qu C, Zou W, Novack DV, Abu-Amer Y, Civitelli R, Mbalaviele G. Alippe Y, et al. Sci Rep. 2017 Jul 26;7(1):6630. doi: 10.1038/s41598-017-07014-0. Sci Rep. 2017. PMID: 28747793 Free PMC article.

2

Activation of peroxisome proliferator-activated receptor-gamma pathway inhibits osteoclast differentiation.

Mbalaviele G, Abu-Amer Y, Meng A, Jaiswal R, Beck S, Pittenger MF, Thiede MA, Marshak DR. Mbalaviele G, et al. J Biol Chem. 2000 May 12;275(19):14388-93. doi: 10.1074/jbc.275.19.14388. J Biol Chem. 2000. PMID: 10799521 Free article.

3

Marrow stromal cells and osteoclast precursors differentially contribute to TNF-alpha-induced osteoclastogenesis in vivo.

Kitaura H, Sands MS, Aya K, Zhou P, Hirayama T, Uthgenannt B, Wei S, Takeshita S, Novack DV, Silva MJ, Abu-Amer Y, Ross FP, Teitelbaum SL. Kitaura H, et al. J Immunol. 2004 Oct 15;173(8):4838-46. doi: 10.4049/jimmunol.173.8.4838. J Immunol. 2004. PMID: 15470024

4

Advances in osteoclast differentiation and function.

Abu-Amer Y. Abu-Amer Y. Curr Drug Targets Immune Endocr Metabol Disord. 2005 Sep;5(3):347-55. doi: 10.2174/1568008054863808. Curr Drug Targets Immune Endocr Metabol Disord. 2005. PMID: 16178795 Review.

5

Inhibition of p38 mitogen-activated protein kinase prevents inflammatory bone destruction.

Mbalaviele G, Anderson G, Jones A, De Ciechi P, Settle S, Mnich S, Thiede M, Abu-Amer Y, Portanova J, Monahan J. Mbalaviele G, et al. J Pharmacol Exp Ther. 2006 Jun;317(3):1044-53. doi: 10.1124/jpet.105.100362. Epub 2006 Feb 24. J Pharmacol Exp Ther. 2006. PMID: 16501068

6

Role of the NF-kappaB axis in immune modulation of osteoclasts and bone loss.

Abu-Amer Y, Darwech I, Otero J. Abu-Amer Y, et al. Autoimmunity. 2008 Apr;41(3):204-11. doi: 10.1080/08916930701694543. Autoimmunity. 2008. PMID: 18365833 Review.

7

IKKbeta activation is sufficient for RANK-independent osteoclast differentiation and osteolysis.

Otero JE, Dai S, Alhawagri MA, Darwech I, Abu-Amer Y. Otero JE, et al. J Bone Miner Res. 2010 Jun;25(6):1282-94. doi: 10.1002/jbmr.4. J Bone Miner Res. 2010. PMID: 20200955 Free PMC article.

8

NF-κB signaling and bone resorption.

Abu-Amer Y. Abu-Amer Y. Osteoporos Int. 2013 Sep;24(9):2377-86. doi: 10.1007/s00198-013-2313-x. Epub 2013 Mar 7. Osteoporos Int. 2013. PMID: 23468073 Free PMC article. Review.

9

Constitutive activation of IKK2/NF-κB impairs osteogenesis and skeletal development.

Swarnkar G, Zhang K, Mbalaviele G, Long F, Abu-Amer Y. Swarnkar G, et al. PLoS One. 2014 Mar 11;9(3):e91421. doi: 10.1371/journal.pone.0091421. eCollection 2014. PLoS One. 2014. PMID: 24618907 Free PMC article.

10

NLRP3 mediates osteolysis through inflammation-dependent and -independent mechanisms.

Qu C, Bonar SL, Hickman-Brecks CL, Abu-Amer S, McGeough MD, Peña CA, Broderick L, Yang C, Grimston SK, Kading J, Abu-Amer Y, Novack DV, Hoffman HM, Civitelli R, Mbalaviele G. Qu C, et al. FASEB J. 2015 Apr;29(4):1269-79. doi: 10.1096/fj.14-264804. Epub 2014 Dec 4. FASEB J. 2015. PMID: 25477279 Free PMC article.

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