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NLRP3 mediates osteolysis through inflammation-dependent and -independent mechanisms.
Qu C, Bonar SL, Hickman-Brecks CL, Abu-Amer S, McGeough MD, Peña CA, Broderick L, Yang C, Grimston SK, Kading J, Abu-Amer Y, Novack DV, Hoffman HM, Civitelli R, Mbalaviele G. Qu C, et al. Among authors: novack dv. FASEB J. 2015 Apr;29(4):1269-79. doi: 10.1096/fj.14-264804. Epub 2014 Dec 4. FASEB J. 2015. PMID: 25477279 Free PMC article.
Osteoclasts-Key Players in Skeletal Health and Disease.
Novack DV, Mbalaviele G. Novack DV, et al. Microbiol Spectr. 2016 Jun;4(3):10.1128/microbiolspec.MCHD-0011-2015. doi: 10.1128/microbiolspec.MCHD-0011-2015. Microbiol Spectr. 2016. PMID: 27337470 Free PMC article. Review.
Inflammatory osteolysis: a conspiracy against bone.
Mbalaviele G, Novack DV, Schett G, Teitelbaum SL. Mbalaviele G, et al. Among authors: novack dv. J Clin Invest. 2017 Jun 1;127(6):2030-2039. doi: 10.1172/JCI93356. Epub 2017 Jun 1. J Clin Invest. 2017. PMID: 28569732 Free PMC article. Review.
Constitutively activated NLRP3 inflammasome causes inflammation and abnormal skeletal development in mice.
Bonar SL, Brydges SD, Mueller JL, McGeough MD, Pena C, Chen D, Grimston SK, Hickman-Brecks CL, Ravindran S, McAlinden A, Novack DV, Kastner DL, Civitelli R, Hoffman HM, Mbalaviele G. Bonar SL, et al. Among authors: novack dv. PLoS One. 2012;7(4):e35979. doi: 10.1371/journal.pone.0035979. Epub 2012 Apr 27. PLoS One. 2012. PMID: 22558291 Free PMC article.
The ADP receptor P2RY12 regulates osteoclast function and pathologic bone remodeling.
Su X, Floyd DH, Hughes A, Xiang J, Schneider JG, Uluckan O, Heller E, Deng H, Zou W, Craft CS, Wu K, Hirbe AC, Grabowska D, Eagleton MC, Townsley S, Collins L, Piwnica-Worms D, Steinberg TH, Novack DV, Conley PB, Hurchla MA, Rogers M, Weilbaecher KN. Su X, et al. Among authors: novack dv. J Clin Invest. 2012 Oct;122(10):3579-92. doi: 10.1172/JCI38576. Epub 2012 Sep 17. J Clin Invest. 2012. PMID: 22996695 Free PMC article.
86 results