Blagg BSJ - Search Results

1

Hsp90 activator Aha1 drives production of pathological tau aggregates.

Shelton LB, Baker JD, Zheng D, Sullivan LE, Solanki PK, Webster JM, Sun Z, Sabbagh JJ, Nordhues BA, Koren J 3rd, Ghosh S, Blagg BSJ, Blair LJ, Dickey CA. Shelton LB, et al. Among authors: blagg bsj. Proc Natl Acad Sci U S A. 2017 Sep 5;114(36):9707-9712. doi: 10.1073/pnas.1707039114. Epub 2017 Aug 21. Proc Natl Acad Sci U S A. 2017. PMID: 28827321 Free PMC article.

2

High-throughput screening for Hsp90 ATPase inhibitors.

Avila C, Hadden MK, Ma Z, Kornilayev BA, Ye QZ, Blagg BS. Avila C, et al. Bioorg Med Chem Lett. 2006 Jun 1;16(11):3005-8. doi: 10.1016/j.bmcl.2006.02.063. Epub 2006 Mar 10. Bioorg Med Chem Lett. 2006. PMID: 16530412

3

Design, synthesis, and structure--activity relationships for chimeric inhibitors of Hsp90.

Shen G, Wang M, Welch TR, Blagg BS. Shen G, et al. J Org Chem. 2006 Sep 29;71(20):7618-31. doi: 10.1021/jo061054f. J Org Chem. 2006. PMID: 16995666

4

Hsp90: a novel target for the disruption of multiple signaling cascades.

Bishop SC, Burlison JA, Blagg BS. Bishop SC, et al. Curr Cancer Drug Targets. 2007 Jun;7(4):369-88. doi: 10.2174/156800907780809778. Curr Cancer Drug Targets. 2007. PMID: 17979631 Review.

5

Gedunin, a novel hsp90 inhibitor: semisynthesis of derivatives and preliminary structure-activity relationships.

Brandt GE, Schmidt MD, Prisinzano TE, Blagg BS. Brandt GE, et al. J Med Chem. 2008 Oct 23;51(20):6495-502. doi: 10.1021/jm8007486. Epub 2008 Sep 25. J Med Chem. 2008. PMID: 18816111 Free PMC article.

6

Novobiocin and additional inhibitors of the Hsp90 C-terminal nucleotide-binding pocket.

Donnelly A, Blagg BS. Donnelly A, et al. Curr Med Chem. 2008;15(26):2702-17. doi: 10.2174/092986708786242895. Curr Med Chem. 2008. PMID: 18991631 Free PMC article. Review.

7

Neuroprotective activity and evaluation of Hsp90 inhibitors in an immortalized neuronal cell line.

Lu Y, Ansar S, Michaelis ML, Blagg BS. Lu Y, et al. Bioorg Med Chem. 2009 Feb 15;17(4):1709-15. doi: 10.1016/j.bmc.2008.12.047. Epub 2008 Dec 25. Bioorg Med Chem. 2009. PMID: 19138859 Free PMC article.

8

Natural product inhibitors of Hsp90: potential leads for drug discovery.

Amolins MW, Blagg BS. Amolins MW, et al. Mini Rev Med Chem. 2009 Feb;9(2):140-52. doi: 10.2174/138955709787316056. Mini Rev Med Chem. 2009. PMID: 19200020 Free PMC article. Review.

9

Alternate strategies of Hsp90 modulation for the treatment of cancer and other diseases.

Brandt GE, Blagg BS. Brandt GE, et al. Curr Top Med Chem. 2009;9(15):1447-61. doi: 10.2174/156802609789895683. Curr Top Med Chem. 2009. PMID: 19860731 Free PMC article. Review.

10

To fold or not to fold: modulation and consequences of Hsp90 inhibition.

Peterson LB, Blagg BS. Peterson LB, et al. Future Med Chem. 2009 May;1(2):267-83. doi: 10.4155/fmc.09.17. Future Med Chem. 2009. PMID: 20161407 Free PMC article. Review.

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