Kahnt A - Search Results

1

A Dual Modulator of Farnesoid X Receptor and Soluble Epoxide Hydrolase To Counter Nonalcoholic Steatohepatitis.

Schmidt J, Rotter M, Weiser T, Wittmann S, Weizel L, Kaiser A, Heering J, Goebel T, Angioni C, Wurglics M, Paulke A, Geisslinger G, Kahnt A, Steinhilber D, Proschak E, Merk D. Schmidt J, et al. Among authors: kahnt a. J Med Chem. 2017 Sep 28;60(18):7703-7724. doi: 10.1021/acs.jmedchem.7b00398. Epub 2017 Sep 8. J Med Chem. 2017. PMID: 28845983

2

Molecular pharmacological profile of a novel thiazolinone-based direct and selective 5-lipoxygenase inhibitor.

Hofmann B, Rödl CB, Kahnt AS, Maier TJ, Michel AA, Hoffmann M, Rau O, Awwad K, Pellowska M, Wurglics M, Wacker M, Zivković A, Fleming I, Schubert-Zsilavecz M, Stark H, Schneider G, Steinhilber D. Hofmann B, et al. Among authors: kahnt as. Br J Pharmacol. 2012 Apr;165(7):2304-13. doi: 10.1111/j.1476-5381.2011.01707.x. Br J Pharmacol. 2012. PMID: 21955369 Free PMC article.

3

Molecular characterization of EP6--a novel imidazo[1,2-a]pyridine based direct 5-lipoxygenase inhibitor.

Wisniewska JM, Rödl CB, Kahnt AS, Buscató El, Ulrich S, Tanrikulu Y, Achenbach J, Rörsch F, Grösch S, Schneider G, Cinatl J Jr, Proschak E, Steinhilber D, Hofmann B. Wisniewska JM, et al. Biochem Pharmacol. 2012 Jan 15;83(2):228-40. doi: 10.1016/j.bcp.2011.10.012. Epub 2011 Oct 18. Biochem Pharmacol. 2012. PMID: 22027220

4

Cysteinyl leukotriene-receptor-1 antagonists interfere with PGE2 synthesis by inhibiting mPGES-1 activity.

Kahnt AS, Rörsch F, Diehl O, Hofmann B, Lehmann C, Steinbrink SD, Angioni C, Geisslinger G, Grösch S, Steinhilber D, Maier TJ. Kahnt AS, et al. Biochem Pharmacol. 2013 Jul 15;86(2):286-96. doi: 10.1016/j.bcp.2013.05.005. Epub 2013 May 14. Biochem Pharmacol. 2013. PMID: 23684692

5

5-Lipoxygenase is a candidate target for therapeutic management of stem cell-like cells in acute myeloid leukemia.

Roos J, Oancea C, Heinssmann M, Khan D, Held H, Kahnt AS, Capelo R, la Buscató E, Proschak E, Puccetti E, Steinhilber D, Fleming I, Maier TJ, Ruthardt M. Roos J, et al. Cancer Res. 2014 Sep 15;74(18):5244-55. doi: 10.1158/0008-5472.CAN-13-3012. Epub 2014 Jul 31. Cancer Res. 2014. PMID: 25082812

6

Chiral chromatography-tandem mass spectrometry applied to the determination of pro-resolving lipid mediators.

Homann J, Lehmann C, Kahnt AS, Steinhilber D, Parnham MJ, Geisslinger G, Ferreirós N. Homann J, et al. J Chromatogr A. 2014 Sep 19;1360:150-63. doi: 10.1016/j.chroma.2014.07.068. Epub 2014 Jul 29. J Chromatogr A. 2014. PMID: 25124229

7

Characterisation of taxlllaids A-G; natural products from Xenorhabdus indica.

Kronenwerth M, Bozhüyük KA, Kahnt AS, Steinhilber D, Gaudriault S, Kaiser M, Bode HB. Kronenwerth M, et al. Among authors: kahnt as. Chemistry. 2014 Dec 22;20(52):17478-87. doi: 10.1002/chem.201403979. Epub 2014 Oct 28. Chemistry. 2014. PMID: 25351611

8

Lipoxin and resolvin biosynthesis is dependent on 5-lipoxygenase activating protein.

Lehmann C, Homann J, Ball AK, Blöcher R, Kleinschmidt TK, Basavarajappa D, Angioni C, Ferreirós N, Häfner AK, Rådmark O, Proschak E, Haeggström JZ, Geisslinger G, Parnham MJ, Steinhilber D, Kahnt AS. Lehmann C, et al. FASEB J. 2015 Dec;29(12):5029-43. doi: 10.1096/fj.15-275487. Epub 2015 Aug 19. FASEB J. 2015. PMID: 26289316

9

AF4 and AF4-MLL mediate transcriptional elongation of 5-lipoxygenase mRNA by 1, 25-dihydroxyvitamin D3.

Ahmad K, Scholz B, Capelo R, Schweighöfer I, Kahnt AS, Marschalek R, Steinhilber D. Ahmad K, et al. Oncotarget. 2015 Sep 22;6(28):25784-800. doi: 10.18632/oncotarget.4703. Oncotarget. 2015. PMID: 26329759 Free PMC article.

10

N-Benzylbenzamides: A Novel Merged Scaffold for Orally Available Dual Soluble Epoxide Hydrolase/Peroxisome Proliferator-Activated Receptor γ Modulators.

Blöcher R, Lamers C, Wittmann SK, Merk D, Hartmann M, Weizel L, Diehl O, Brüggerhoff A, Boß M, Kaiser A, Schader T, Göbel T, Grundmann M, Angioni C, Heering J, Geisslinger G, Wurglics M, Kostenis E, Brüne B, Steinhilber D, Schubert-Zsilavecz M, Kahnt AS, Proschak E. Blöcher R, et al. Among authors: kahnt as. J Med Chem. 2016 Jan 14;59(1):61-81. doi: 10.1021/acs.jmedchem.5b01239. Epub 2015 Dec 25. J Med Chem. 2016. PMID: 26595749

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