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PDE1A inhibition elicits cGMP-dependent relaxation of rat mesenteric arteries.
Khammy MM, Dalsgaard T, Larsen PH, Christoffersen CT, Clausen D, Rasmussen LK, Folkersen L, Grunnet M, Kehler J, Aalkjaer C, Nielsen J. Khammy MM, et al. Among authors: nielsen j. Br J Pharmacol. 2017 Nov;174(22):4186-4198. doi: 10.1111/bph.14034. Epub 2017 Oct 15. Br J Pharmacol. 2017. PMID: 28910498 Free PMC article.
Triazoloquinazolines as a novel class of phosphodiesterase 10A (PDE10A) inhibitors.
Kehler J, Ritzen A, Langgård M, Petersen SL, Farah MM, Bundgaard C, Christoffersen CT, Nielsen J, Kilburn JP. Kehler J, et al. Among authors: nielsen j. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3738-42. doi: 10.1016/j.bmcl.2011.04.067. Epub 2011 Apr 30. Bioorg Med Chem Lett. 2011. PMID: 21602043
A mouse model of the schizophrenia-associated 1q21.1 microdeletion syndrome exhibits altered mesolimbic dopamine transmission.
Nielsen J, Fejgin K, Sotty F, Nielsen V, Mørk A, Christoffersen CT, Yavich L, Lauridsen JB, Clausen D, Larsen PH, Egebjerg J, Werge TM, Kallunki P, Christensen KV, Didriksen M. Nielsen J, et al. Among authors: nielsen v. Transl Psychiatry. 2017 Nov 30;7(11):1261. doi: 10.1038/s41398-017-0011-8. Transl Psychiatry. 2017. PMID: 29187755 Free PMC article.
Discovery and development of 11C-Lu AE92686 as a radioligand for PET imaging of phosphodiesterase10A in the brain.
Kehler J, Kilburn JP, Estrada S, Christensen SR, Wall A, Thibblin A, Lubberink M, Bundgaard C, Brennum LT, Steiniger-Brach B, Christoffersen CT, Timmermann S, Kreilgaard M, Antoni G, Bang-Andersen B, Nielsen J. Kehler J, et al. Among authors: nielsen j. J Nucl Med. 2014 Sep;55(9):1513-8. doi: 10.2967/jnumed.114.140178. Epub 2014 Jul 3. J Nucl Med. 2014. PMID: 24994928 Free article.
The multimodal antidepressant vortioxetine may facilitate pyramidal cell firing by inhibition of 5-HT3 receptor expressing interneurons: An in vitro study in rat hippocampus slices.
Dale E, Grunnet M, Pehrson AL, Frederiksen K, Larsen PH, Nielsen J, Stensbøl TB, Ebert B, Yin H, Lu D, Liu H, Jensen TN, Yang CR, Sanchez C. Dale E, et al. Among authors: nielsen j. Brain Res. 2018 Jun 15;1689:1-11. doi: 10.1016/j.brainres.2017.12.025. Epub 2017 Dec 21. Brain Res. 2018. PMID: 29274875
Comparison of quantitative trait loci methods: Total expression and allelic imbalance method in brain RNA-seq.
Gådin JR, Buil A, Colantuoni C, Jaffe AE, Nielsen J, Shin JH, Hyde TM, Kleinman JE; BrainSeq Consortium; Plath N, Eriksson P, Brunak S, Didriksen M, Weinberger DR, Folkersen L. Gådin JR, et al. Among authors: nielsen j. PLoS One. 2019 Jun 17;14(6):e0217765. doi: 10.1371/journal.pone.0217765. eCollection 2019. PLoS One. 2019. PMID: 31206532 Free PMC article.
7,443 results