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Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone.
Lutsik P, Baude A, Mancarella D, Öz S, Kühn A, Toth R, Hey J, Toprak UH, Lim J, Nguyen VH, Jiang C, Mayakonda A, Hartmann M, Rosemann F, Breuer K, Vonficht D, Grünschläger F, Lee S, Schuhmacher MK, Kusevic D, Jauch A, Weichenhan D, Zustin J, Schlesner M, Haas S, Park JH, Park YJ, Oppermann U, Jeltsch A, Haller F, Fellenberg J, Lindroth AM, Plass C. Lutsik P, et al. Among authors: baude a. Nat Commun. 2020 Oct 27;11(1):5414. doi: 10.1038/s41467-020-18955-y. Nat Commun. 2020. PMID: 33110075 Free PMC article.
Histone 3.3 hotspot mutations in conventional osteosarcomas: a comprehensive clinical and molecular characterization of six H3F3A mutated cases.
Koelsche C, Schrimpf D, Tharun L, Roth E, Sturm D, Jones DTW, Renker EK, Sill M, Baude A, Sahm F, Capper D, Bewerunge-Hudler M, Hartmann W, Kulozik AE, Petersen I, Flucke U, Schreuder HWB, Büttner R, Weber MA, Schirmacher P, Plass C, Pfister SM, von Deimling A, Mechtersheimer G. Koelsche C, et al. Among authors: baude a. Clin Sarcoma Res. 2017 May 4;7:9. doi: 10.1186/s13569-017-0075-5. eCollection 2017. Clin Sarcoma Res. 2017. PMID: 28484590 Free PMC article.
LEDGF (p75) promotes DNA-end resection and homologous recombination.
Daugaard M, Baude A, Fugger K, Povlsen LK, Beck H, Sørensen CS, Petersen NH, Sorensen PH, Lukas C, Bartek J, Lukas J, Rohde M, Jäättelä M. Daugaard M, et al. Among authors: baude a. Nat Struct Mol Biol. 2012 Aug;19(8):803-10. doi: 10.1038/nsmb.2314. Epub 2012 Jul 8. Nat Struct Mol Biol. 2012. PMID: 22773103
61 results