Unger TL - Search Results

1

A Dementia-Associated Risk Variant near TMEM106B Alters Chromatin Architecture and Gene Expression.

Gallagher MD, Posavi M, Huang P, Unger TL, Berlyand Y, Gruenewald AL, Chesi A, Manduchi E, Wells AD, Grant SFA, Blobel GA, Brown CD, Chen-Plotkin AS. Gallagher MD, et al. Among authors: unger tl. Am J Hum Genet. 2017 Nov 2;101(5):643-663. doi: 10.1016/j.ajhg.2017.09.004. Epub 2017 Oct 19. Am J Hum Genet. 2017. PMID: 29056226 Free PMC article.

2

Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies.

Igaz LM, Kwong LK, Chen-Plotkin A, Winton MJ, Unger TL, Xu Y, Neumann M, Trojanowski JQ, Lee VM. Igaz LM, et al. Among authors: unger tl. J Biol Chem. 2009 Mar 27;284(13):8516-24. doi: 10.1074/jbc.M809462200. Epub 2009 Jan 21. J Biol Chem. 2009. PMID: 19164285 Free PMC article.

3

Brain progranulin expression in GRN-associated frontotemporal lobar degeneration.

Chen-Plotkin AS, Xiao J, Geser F, Martinez-Lage M, Grossman M, Unger T, Wood EM, Van Deerlin VM, Trojanowski JQ, Lee VM. Chen-Plotkin AS, et al. Acta Neuropathol. 2010 Jan;119(1):111-22. doi: 10.1007/s00401-009-0576-2. Epub 2009 Aug 2. Acta Neuropathol. 2010. PMID: 19649643 Free PMC article.

4

Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice.

Igaz LM, Kwong LK, Lee EB, Chen-Plotkin A, Swanson E, Unger T, Malunda J, Xu Y, Winton MJ, Trojanowski JQ, Lee VM. Igaz LM, et al. J Clin Invest. 2011 Feb;121(2):726-38. doi: 10.1172/JCI44867. Epub 2011 Jan 4. J Clin Invest. 2011. PMID: 21206091 Free PMC article.

5

TMEM106B, the risk gene for frontotemporal dementia, is regulated by the microRNA-132/212 cluster and affects progranulin pathways.

Chen-Plotkin AS, Unger TL, Gallagher MD, Bill E, Kwong LK, Volpicelli-Daley L, Busch JI, Akle S, Grossman M, Van Deerlin V, Trojanowski JQ, Lee VM. Chen-Plotkin AS, et al. Among authors: unger tl. J Neurosci. 2012 Aug 15;32(33):11213-27. doi: 10.1523/JNEUROSCI.0521-12.2012. J Neurosci. 2012. PMID: 22895706 Free PMC article.

6

Lower plasma apolipoprotein A1 levels are found in Parkinson's disease and associate with apolipoprotein A1 genotype.

Swanson CR, Li K, Unger TL, Gallagher MD, Van Deerlin VM, Agarwal P, Leverenz J, Roberts J, Samii A, Gross RG, Hurtig H, Rick J, Weintraub D, Trojanowski JQ, Zabetian C, Chen-Plotkin AS. Swanson CR, et al. Among authors: unger tl. Mov Disord. 2015 May;30(6):805-12. doi: 10.1002/mds.26022. Epub 2014 Sep 16. Mov Disord. 2015. PMID: 25227208 Free PMC article.

7

Increased expression of the frontotemporal dementia risk factor TMEM106B causes C9orf72-dependent alterations in lysosomes.

Busch JI, Unger TL, Jain N, Tyler Skrinak R, Charan RA, Chen-Plotkin AS. Busch JI, et al. Among authors: unger tl. Hum Mol Genet. 2016 Jul 1;25(13):2681-2697. doi: 10.1093/hmg/ddw127. Epub 2016 Apr 28. Hum Mol Genet. 2016. PMID: 27126638 Free PMC article.

8

Plasma EGF and cognitive decline in Parkinson's disease and Alzheimer's disease.

Lim NS, Swanson CR, Cherng HR, Unger TL, Xie SX, Weintraub D, Marek K, Stern MB, Siderowf A; PARS Investigators; Alzheimer's Disease Neuroimaging Initiative; Trojanowski JQ, Chen-Plotkin AS. Lim NS, et al. Among authors: unger tl. Ann Clin Transl Neurol. 2016 Mar 29;3(5):346-55. doi: 10.1002/acn3.299. eCollection 2016 May. Ann Clin Transl Neurol. 2016. PMID: 27231704 Free PMC article.

9

Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity.

Chung CY, Berson A, Kennerdell JR, Sartoris A, Unger T, Porta S, Kim HJ, Smith ER, Shilatifard A, Van Deerlin V, Lee VM, Chen-Plotkin A, Bonini NM. Chung CY, et al. Nat Commun. 2018 Oct 23;9(1):4406. doi: 10.1038/s41467-018-06543-0. Nat Commun. 2018. PMID: 30353006 Free PMC article.

10

Author Correction: Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity.

Chung CY, Berson A, Kennerdell JR, Sartoris A, Unger T, Porta S, Kim HJ, Smith ER, Shilatifard A, Van Deerlin V, Lee VM, Chen-Plotkin A, Bonini NM. Chung CY, et al. Nat Commun. 2019 Jan 29;10(1):555. doi: 10.1038/s41467-019-08562-x. Nat Commun. 2019. PMID: 30696825 Free PMC article.

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