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A member of the gut mycobiota modulates host purine metabolism exacerbating colitis in mice.
Chiaro TR, Soto R, Zac Stephens W, Kubinak JL, Petersen C, Gogokhia L, Bell R, Delgado JC, Cox J, Voth W, Brown J, Stillman DJ, O'Connell RM, Tebo AE, Round JL. Chiaro TR, et al. Among authors: round jl. Sci Transl Med. 2017 Mar 8;9(380):eaaf9044. doi: 10.1126/scitranslmed.aaf9044. Sci Transl Med. 2017. PMID: 28275154 Free PMC article.
Microbiota promotes systemic T-cell survival through suppression of an apoptotic factor.
Soto R, Petersen C, Novis CL, Kubinak JL, Bell R, Stephens WZ, Lane TE, Fujinami RS, Bosque A, O'Connell RM, Round JL. Soto R, et al. Among authors: round jl. Proc Natl Acad Sci U S A. 2017 May 23;114(21):5497-5502. doi: 10.1073/pnas.1619336114. Epub 2017 May 9. Proc Natl Acad Sci U S A. 2017. PMID: 28487480 Free PMC article.
Antitumor immunity is defective in T cell-specific microRNA-155-deficient mice and is rescued by immune checkpoint blockade.
Huffaker TB, Lee SH, Tang WW, Wallace JA, Alexander M, Runtsch MC, Larsen DK, Thompson J, Ramstead AG, Voth WP, Hu R, Round JL, Williams MA, O'Connell RM. Huffaker TB, et al. Among authors: round jl. J Biol Chem. 2017 Nov 10;292(45):18530-18541. doi: 10.1074/jbc.M117.808121. Epub 2017 Sep 14. J Biol Chem. 2017. PMID: 28912267 Free PMC article.
88 results