Sorf A - Search Results

1

In vitro and in silico Evaluation of Non-Quaternary Reactivators of AChE as Antidotes of Organophosphorus Poisoning - a New Hope or a Blind Alley?

Soukup O, Korabecny J, Malinak D, Nepovimova E, Pham NL, Musilek K, Hrabinova M, Hepnarova V, Dolezal R, Pavek P, Jost P, Kobrlova T, Jankockova J, Gorecki L, Psotka M, Nguyen TD, Box K, Outhwaite B, Ceckova M, Sorf A, Jun D, Kuca K. Soukup O, et al. Among authors: sorf a. Med Chem. 2018;14(3):281-292. doi: 10.2174/1573406414666180112105657. Med Chem. 2018. PMID: 29332594

2

Dabrafenib inhibits ABCG2 and cytochrome P450 isoenzymes; potential implications for combination anticancer therapy.

Sorf A, Vagiannis D, Ahmed F, Hofman J, Ceckova M. Sorf A, et al. Toxicol Appl Pharmacol. 2022 Jan 1;434:115797. doi: 10.1016/j.taap.2021.115797. Epub 2021 Nov 13. Toxicol Appl Pharmacol. 2022. PMID: 34780725

3

Ribociclib shows potential for pharmacokinetic drug-drug interactions being a substrate of ABCB1 and potent inhibitor of ABCB1, ABCG2 and CYP450 isoforms in vitro.

Sorf A, Hofman J, Kučera R, Staud F, Ceckova M. Sorf A, et al. Biochem Pharmacol. 2018 Aug;154:10-17. doi: 10.1016/j.bcp.2018.04.013. Epub 2018 Apr 16. Biochem Pharmacol. 2018. PMID: 29673999

4

Cyclin-dependent kinase inhibitors AZD5438 and R547 show potential for enhancing efficacy of daunorubicin-based anticancer therapy: Interaction with carbonyl-reducing enzymes and ABC transporters.

Sorf A, Novotna E, Hofman J, Morell A, Staud F, Wsol V, Ceckova M. Sorf A, et al. Biochem Pharmacol. 2019 May;163:290-298. doi: 10.1016/j.bcp.2019.02.035. Epub 2019 Feb 28. Biochem Pharmacol. 2019. PMID: 30826329

5

Interactions between Maraviroc and the ABCB1, ABCG2, and ABCC2 Transporters: An Important Role in Transplacental Pharmacokinetics.

Tupova L, Ceckova M, Ambrus C, Sorf A, Ptackova Z, Gaborik Z, Staud F. Tupova L, et al. Among authors: sorf a. Drug Metab Dispos. 2019 Sep;47(9):954-960. doi: 10.1124/dmd.119.087684. Epub 2019 Jul 2. Drug Metab Dispos. 2019. PMID: 31266750

6

ABCB1 as a potential beneficial target of midostaurin in acute myeloid leukemia.

Sucha S, Sorf A, Svoren M, Vagiannis D, Ahmed F, Visek B, Ceckova M. Sucha S, et al. Among authors: sorf a. Biomed Pharmacother. 2022 Jun;150:112962. doi: 10.1016/j.biopha.2022.112962. Epub 2022 Apr 21. Biomed Pharmacother. 2022. PMID: 35462331 Free article.

7

Brivanib Exhibits Potential for Pharmacokinetic Drug-Drug Interactions and the Modulation of Multidrug Resistance through the Inhibition of Human ABCG2 Drug Efflux Transporter and CYP450 Biotransformation Enzymes.

Hofman J, Sorf A, Vagiannis D, Sucha S, Kammerer S, Küpper JH, Chen S, Guo L, Ceckova M, Staud F. Hofman J, et al. Among authors: sorf a. Mol Pharm. 2019 Nov 4;16(11):4436-4450. doi: 10.1021/acs.molpharmaceut.9b00361. Epub 2019 Oct 21. Mol Pharm. 2019. PMID: 31633365

8

Interactions of Alectinib with Human ATP-Binding Cassette Drug Efflux Transporters and Cytochrome P450 Biotransformation Enzymes: Effect on Pharmacokinetic Multidrug Resistance.

Hofman J, Sorf A, Vagiannis D, Sucha S, Novotna E, Kammerer S, Küpper JH, Ceckova M, Staud F. Hofman J, et al. Among authors: sorf a. Drug Metab Dispos. 2019 Jul;47(7):699-709. doi: 10.1124/dmd.119.086975. Epub 2019 May 8. Drug Metab Dispos. 2019. PMID: 31068367

9

Targeting Pharmacokinetic Drug Resistance in Acute Myeloid Leukemia Cells with CDK4/6 Inhibitors.

Sorf A, Sucha S, Morell A, Novotna E, Staud F, Zavrelova A, Visek B, Wsol V, Ceckova M. Sorf A, et al. Cancers (Basel). 2020 Jun 16;12(6):1596. doi: 10.3390/cancers12061596. Cancers (Basel). 2020. PMID: 32560251 Free PMC article.

10

S-(4-Nitrobenzyl)-6-thioinosine (NBMPR) is Not a Selective Inhibitor of Equilibrative Nucleoside Transporters but Also Blocks Efflux Activity of Breast Cancer Resistance Protein.

Karbanova S, Sorf A, Jiraskova L, Lalinska A, Ptackova Z, Staud F, Cerveny L. Karbanova S, et al. Among authors: sorf a. Pharm Res. 2020 Feb 21;37(3):58. doi: 10.1007/s11095-020-2782-5. Pharm Res. 2020. PMID: 32086630

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