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Page 1
MS AHI1 genetic risk promotes IFNγ+ CD4+ T cells.
Kaskow BJ, Buttrick TS, Klein HU, White C, Bourgeois JR, Ferland RJ, Patsopoulos N, Bradshaw EM, De Jager PL, Elyaman W. Kaskow BJ, et al. Among authors: de jager pl. Neurol Neuroimmunol Neuroinflamm. 2017 Dec 8;5(1):e414. doi: 10.1212/NXI.0000000000000414. eCollection 2018 Jan. Neurol Neuroimmunol Neuroinflamm. 2017. PMID: 29379820 Free PMC article.
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.
Patsopoulos NA; Bayer Pharma MS Genetics Working Group; Steering Committees of Studies Evaluating IFNβ-1b and a CCR1-Antagonist; ANZgene Consortium; GeneMSA; International Multiple Sclerosis Genetics Consortium; Esposito F, Reischl J, Lehr S, Bauer D, Heubach J, Sandbrink R, Pohl C, Edan G, Kappos L, Miller D, Montalbán J, Polman CH, Freedman MS, Hartung HP, Arnason BG, Comi G, Cook S, Filippi M, Goodin DS, Jeffery D, O'Connor P, Ebers GC, Langdon D, Reder AT, Traboulsee A, Zipp F, Schimrigk S, Hillert J, Bahlo M, Booth DR, Broadley S, Brown MA, Browning BL, Browning SR, Butzkueven H, Carroll WM, Chapman C, Foote SJ, Griffiths L, Kermode AG, Kilpatrick TJ, Lechner-Scott J, Marriott M, Mason D, Moscato P, Heard RN, Pender MP, Perreau VM, Perera D, Rubio JP, Scott RJ, Slee M, Stankovich J, Stewart GJ, Taylor BV, Tubridy N, Willoughby E, Wiley J, Matthews P, Boneschi FM, Compston A, Haines J, Hauser SL, McCauley J, Ivinson A, Oksenberg JR, Pericak-Vance M, Sawcer SJ, De Jager PL, Hafler DA, de Bakker PI. Patsopoulos NA, et al. Among authors: de jager pl, de bakker pi. Ann Neurol. 2011 Dec;70(6):897-912. doi: 10.1002/ana.22609. Ann Neurol. 2011. PMID: 22190364 Free PMC article.
Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles.
Mero IL, Gustavsen MW, Sæther HS, Flåm ST, Berg-Hansen P, Søndergaard HB, Jensen PE, Berge T, Bjølgerud A, Muggerud A, Aarseth JH; International Multiple Sclerosis Genetics Consortium; Myhr KM, Celius EG, Sellebjerg F, Hillert J, Alfredsson L, Olsson T, Oturai AB, Kockum I, Lie BA, Andreassen BK, Harbo HF. Mero IL, et al. PLoS One. 2013;8(3):e58352. doi: 10.1371/journal.pone.0058352. Epub 2013 Mar 5. PLoS One. 2013. PMID: 23472185 Free PMC article.
CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology.
Bradshaw EM, Chibnik LB, Keenan BT, Ottoboni L, Raj T, Tang A, Rosenkrantz LL, Imboywa S, Lee M, Von Korff A; Alzheimer Disease Neuroimaging Initiative; Morris MC, Evans DA, Johnson K, Sperling RA, Schneider JA, Bennett DA, De Jager PL. Bradshaw EM, et al. Among authors: de jager pl. Nat Neurosci. 2013 Jul;16(7):848-50. doi: 10.1038/nn.3435. Epub 2013 May 23. Nat Neurosci. 2013. PMID: 23708142 Free PMC article.
Genetic susceptibility for Alzheimer disease neuritic plaque pathology.
Shulman JM, Chen K, Keenan BT, Chibnik LB, Fleisher A, Thiyyagura P, Roontiva A, McCabe C, Patsopoulos NA, Corneveaux JJ, Yu L, Huentelman MJ, Evans DA, Schneider JA, Reiman EM, De Jager PL, Bennett DA. Shulman JM, et al. Among authors: de jager pl. JAMA Neurol. 2013 Sep 1;70(9):1150-7. doi: 10.1001/jamaneurol.2013.2815. JAMA Neurol. 2013. PMID: 23836404 Free PMC article.
No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis.
Goris A, van Setten J, Diekstra F, Ripke S, Patsopoulos NA, Sawcer SJ; International Multiple Sclerosis Genetics Consortium; van Es M; Australia and New Zealand MS Genetics Consortium; Andersen PM, Melki J, Meininger V, Hardiman O, Landers JE, Brown RH Jr, Shatunov A, Leigh N, Al-Chalabi A, Shaw CE, Traynor BJ, Chiò A, Restagno G, Mora G, Ophoff RA, Oksenberg JR, Van Damme P, Compston A, Robberecht W, Dubois B, van den Berg LH, De Jager PL, Veldink JH, de Bakker PI. Goris A, et al. Among authors: de jager pl, de bakker pi. Hum Mol Genet. 2014 Apr 1;23(7):1916-22. doi: 10.1093/hmg/ddt574. Epub 2013 Nov 13. Hum Mol Genet. 2014. PMID: 24234648 Free PMC article.
Fine-mapping the genetic association of the major histocompatibility complex in multiple sclerosis: HLA and non-HLA effects.
Patsopoulos NA, Barcellos LF, Hintzen RQ, Schaefer C, van Duijn CM, Noble JA, Raj T; IMSGC; ANZgene; Gourraud PA, Stranger BE, Oksenberg J, Olsson T, Taylor BV, Sawcer S, Hafler DA, Carrington M, De Jager PL, de Bakker PI. Patsopoulos NA, et al. Among authors: de jager pl, de bakker pi. PLoS Genet. 2013 Nov;9(11):e1003926. doi: 10.1371/journal.pgen.1003926. Epub 2013 Nov 21. PLoS Genet. 2013. PMID: 24278027 Free PMC article.
Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci.
Andreassen OA, Harbo HF, Wang Y, Thompson WK, Schork AJ, Mattingsdal M, Zuber V, Bettella F, Ripke S, Kelsoe JR, Kendler KS, O'Donovan MC, Sklar P; Psychiatric Genomics Consortium (PGC) Bipolar Disorder and Schizophrenia Work Groups; International Multiple Sclerosis Genetics Consortium (IMSGC); McEvoy LK, Desikan RS, Lie BA, Djurovic S, Dale AM. Andreassen OA, et al. Mol Psychiatry. 2015 Feb;20(2):207-14. doi: 10.1038/mp.2013.195. Epub 2014 Jan 28. Mol Psychiatry. 2015. PMID: 24468824 Free PMC article.
Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes.
Raj T, Rothamel K, Mostafavi S, Ye C, Lee MN, Replogle JM, Feng T, Lee M, Asinovski N, Frohlich I, Imboywa S, Von Korff A, Okada Y, Patsopoulos NA, Davis S, McCabe C, Paik HI, Srivastava GP, Raychaudhuri S, Hafler DA, Koller D, Regev A, Hacohen N, Mathis D, Benoist C, Stranger BE, De Jager PL. Raj T, et al. Among authors: de jager pl. Science. 2014 May 2;344(6183):519-23. doi: 10.1126/science.1249547. Science. 2014. PMID: 24786080 Free PMC article.
597 results