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Recapitulating the clinical scenario of BRCA-associated pancreatic cancer in pre-clinical models.
Golan T, Stossel C, Atias D, Buzhor E, Halperin S, Cohen K, Raitses-Gurevich M, Glick Y, Raskin S, Yehuda D, Feldman A, Schvimer M, Friedman E, Karni R, Wilson JM, Denroche RE, Lungu I, Bartlett JMS, Mbabaali F, Gallinger S, Berger R. Golan T, et al. Among authors: karni r. Int J Cancer. 2018 Jul 1;143(1):179-183. doi: 10.1002/ijc.31292. Epub 2018 Feb 23. Int J Cancer. 2018. PMID: 29396858
RBFOX2 modulates a metastatic signature of alternative splicing in pancreatic cancer.
Jbara A, Lin KT, Stossel C, Siegfried Z, Shqerat H, Amar-Schwartz A, Elyada E, Mogilevsky M, Raitses-Gurevich M, Johnson JL, Yaron TM, Ovadia O, Jang GH, Danan-Gotthold M, Cantley LC, Levanon EY, Gallinger S, Krainer AR, Golan T, Karni R. Jbara A, et al. Among authors: karni r. Nature. 2023 May;617(7959):147-153. doi: 10.1038/s41586-023-05820-3. Epub 2023 Mar 22. Nature. 2023. PMID: 36949200 Free PMC article.
The role of alternative splicing in cancer drug resistance.
Siegfried Z, Karni R. Siegfried Z, et al. Among authors: karni r. Curr Opin Genet Dev. 2018 Feb;48:16-21. doi: 10.1016/j.gde.2017.10.001. Epub 2017 Nov 5. Curr Opin Genet Dev. 2018. PMID: 29080552 Review.
TRPM2 Mediates Neutrophil Killing of Disseminated Tumor Cells.
Gershkovitz M, Caspi Y, Fainsod-Levi T, Katz B, Michaeli J, Khawaled S, Lev S, Polyansky L, Shaul ME, Sionov RV, Cohen-Daniel L, Aqeilan RI, Shaul YD, Mori Y, Karni R, Fridlender ZG, Binshtok AM, Granot Z. Gershkovitz M, et al. Among authors: karni r. Cancer Res. 2018 May 15;78(10):2680-2690. doi: 10.1158/0008-5472.CAN-17-3614. Epub 2018 Feb 28. Cancer Res. 2018. PMID: 29490946
Alternative Splicing of the Inhibitory Immune Checkpoint Receptor SLAMF6 Generates a Dominant Positive Form, Boosting T-cell Effector Functions.
Hajaj E, Zisman E, Tzaban S, Merims S, Cohen J, Klein S, Frankenburg S, Sade-Feldman M, Tabach Y, Yizhak K, Navon A, Stepensky P, Hacohen N, Peretz T, Veillette A, Karni R, Eisenberg G, Lotem M. Hajaj E, et al. Among authors: karni r. Cancer Immunol Res. 2021 Jun;9(6):637-650. doi: 10.1158/2326-6066.CIR-20-0800. Epub 2021 Mar 24. Cancer Immunol Res. 2021. PMID: 33762352
98 results