Claridge TDW - Search Results

1

Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials.

Yeh TL, Leissing TM, Abboud MI, Thinnes CC, Atasoylu O, Holt-Martyn JP, Zhang D, Tumber A, Lippl K, Lohans CT, Leung IKH, Morcrette H, Clifton IJ, Claridge TDW, Kawamura A, Flashman E, Lu X, Ratcliffe PJ, Chowdhury R, Pugh CW, Schofield CJ. Yeh TL, et al. Among authors: claridge tdw. Chem Sci. 2017 Nov 1;8(11):7651-7668. doi: 10.1039/c7sc02103h. Epub 2017 Sep 11. Chem Sci. 2017. PMID: 29435217 Free PMC article.

2

Comments on the use of a dichromophoric circular dichroism assay for the identification of beta-turns in peptides.

Baldwin JE, Claridge TD, Hulme C, Rodger A, Schofield CJ. Baldwin JE, et al. Int J Pept Protein Res. 1994 Feb;43(2):180-3. doi: 10.1111/j.1399-3011.1994.tb00520.x. Int J Pept Protein Res. 1994. PMID: 8200737

3

Studies on phytanoyl-CoA 2-hydroxylase and synthesis of phytanoyl-coenzyme A.

Kershaw NJ, Mukherji M, MacKinnon CH, Claridge TD, Odell B, Wierzbicki AS, Lloyd MD, Schofield CJ. Kershaw NJ, et al. Bioorg Med Chem Lett. 2001 Sep 17;11(18):2545-8. doi: 10.1016/s0960-894x(01)00494-2. Bioorg Med Chem Lett. 2001. PMID: 11549466

4

Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL.

Hon WC, Wilson MI, Harlos K, Claridge TD, Schofield CJ, Pugh CW, Maxwell PH, Ratcliffe PJ, Stuart DI, Jones EY. Hon WC, et al. Nature. 2002 Jun 27;417(6892):975-8. doi: 10.1038/nature00767. Epub 2002 Jun 5. Nature. 2002. PMID: 12050673

5

Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the beta-carbon of asparagine-803.

McNeill LA, Hewitson KS, Claridge TD, Seibel JF, Horsfall LE, Schofield CJ. McNeill LA, et al. Biochem J. 2002 Nov 1;367(Pt 3):571-5. doi: 10.1042/BJ20021162. Biochem J. 2002. PMID: 12215170 Free PMC article.

6

Evidence for oxidation at C-3 of the flavonoid C-ring during anthocyanin biosynthesis.

Welford RW, Turnbull JJ, Claridge TD, Prescott AG, Schofield CJ. Welford RW, et al. Chem Commun (Camb). 2001 Sep 21;(18):1828-9. doi: 10.1039/b105576n. Chem Commun (Camb). 2001. PMID: 12240335

7

Hypoxia-inducible factor prolyl hydroxylase 2 has a high affinity for ferrous iron and 2-oxoglutarate.

McNeill LA, Flashman E, Buck MR, Hewitson KS, Clifton IJ, Jeschke G, Claridge TD, Ehrismann D, Oldham NJ, Schofield CJ. McNeill LA, et al. Mol Biosyst. 2005 Oct;1(4):321-4. doi: 10.1039/b511249b. Epub 2005 Aug 22. Mol Biosyst. 2005. PMID: 16880998

8

Thioester hydrolysis and C-C bond formation by carboxymethylproline synthase from the crotonase superfamily.

Batchelar ET, Hamed RB, Ducho C, Claridge TD, Edelmann MJ, Kessler B, Schofield CJ. Batchelar ET, et al. Angew Chem Int Ed Engl. 2008;47(48):9322-5. doi: 10.1002/anie.200803906. Angew Chem Int Ed Engl. 2008. PMID: 18972478 No abstract available.

9

Synthesis and conformational analysis of cyclic analogues of inverse gamma-turns.

Kaewpet M, Odell B, King MA, Banerji B, Schofield CJ, Claridge TD. Kaewpet M, et al. Org Biomol Chem. 2008 Oct 7;6(19):3476-85. doi: 10.1039/b808954j. Epub 2008 Aug 7. Org Biomol Chem. 2008. PMID: 19082148

10

Evidence that thienamycin biosynthesis proceeds via C-5 epimerization: ThnE catalyzes the formation of (2S,5S)-trans-carboxymethylproline.

Hamed RB, Batchelar ET, Mecinović J, Claridge TD, Schofield CJ. Hamed RB, et al. Chembiochem. 2009 Jan 26;10(2):246-50. doi: 10.1002/cbic.200800652. Chembiochem. 2009. PMID: 19090510 No abstract available.

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