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ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia.
Wan L, Wen H, Li Y, Lyu J, Xi Y, Hoshii T, Joseph JK, Wang X, Loh YE, Erb MA, Souza AL, Bradner JE, Shen L, Li W, Li H, Allis CD, Armstrong SA, Shi X. Wan L, et al. Among authors: wang x. Nature. 2017 Mar 9;543(7644):265-269. doi: 10.1038/nature21687. Epub 2017 Mar 1. Nature. 2017. PMID: 28241141 Free PMC article.
Recognition of Histone H3K14 Acylation by MORF.
Klein BJ, Simithy J, Wang X, Ahn J, Andrews FH, Zhang Y, Côté J, Shi X, Garcia BA, Kutateladze TG. Klein BJ, et al. Among authors: wang x. Structure. 2017 Apr 4;25(4):650-654.e2. doi: 10.1016/j.str.2017.02.003. Epub 2017 Mar 9. Structure. 2017. PMID: 28286003 Free PMC article.
YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer.
Mi W, Guan H, Lyu J, Zhao D, Xi Y, Jiang S, Andrews FH, Wang X, Gagea M, Wen H, Tora L, Dent SYR, Kutateladze TG, Li W, Li H, Shi X. Mi W, et al. Among authors: wang x. Nat Commun. 2017 Oct 20;8(1):1088. doi: 10.1038/s41467-017-01173-4. Nat Commun. 2017. PMID: 29057918 Free PMC article.
Histone H3K23-specific acetylation by MORF is coupled to H3K14 acylation.
Klein BJ, Jang SM, Lachance C, Mi W, Lyu J, Sakuraba S, Krajewski K, Wang WW, Sidoli S, Liu J, Zhang Y, Wang X, Warfield BM, Kueh AJ, Voss AK, Thomas T, Garcia BA, Liu WR, Strahl BD, Kono H, Li W, Shi X, Côté J, Kutateladze TG. Klein BJ, et al. Among authors: wang x, wang ww. Nat Commun. 2019 Oct 17;10(1):4724. doi: 10.1038/s41467-019-12551-5. Nat Commun. 2019. PMID: 31624313 Free PMC article.
Impaired cell fate through gain-of-function mutations in a chromatin reader.
Wan L, Chong S, Xuan F, Liang A, Cui X, Gates L, Carroll TS, Li Y, Feng L, Chen G, Wang SP, Ortiz MV, Daley SK, Wang X, Xuan H, Kentsis A, Muir TW, Roeder RG, Li H, Li W, Tjian R, Wen H, Allis CD. Wan L, et al. Among authors: wang x, wang sp. Nature. 2020 Jan;577(7788):121-126. doi: 10.1038/s41586-019-1842-7. Epub 2019 Dec 18. Nature. 2020. PMID: 31853060 Free PMC article.
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