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Novosphingobium aromaticivorans uses a Nu-class glutathione S-transferase as a glutathione lyase in breaking the β-aryl ether bond of lignin.
Kontur WS, Bingman CA, Olmsted CN, Wassarman DR, Ulbrich A, Gall DL, Smith RW, Yusko LM, Fox BG, Noguera DR, Coon JJ, Donohue TJ. Kontur WS, et al. Among authors: olmsted cn. J Biol Chem. 2018 Apr 6;293(14):4955-4968. doi: 10.1074/jbc.RA117.001268. Epub 2018 Feb 15. J Biol Chem. 2018. PMID: 29449375 Free PMC article.
A heterodimeric glutathione S-transferase that stereospecifically breaks lignin's β(R)-aryl ether bond reveals the diversity of bacterial β-etherases.
Kontur WS, Olmsted CN, Yusko LM, Niles AV, Walters KA, Beebe ET, Vander Meulen KA, Karlen SD, Gall DL, Noguera DR, Donohue TJ. Kontur WS, et al. Among authors: olmsted cn. J Biol Chem. 2019 Feb 8;294(6):1877-1890. doi: 10.1074/jbc.RA118.006548. Epub 2018 Dec 12. J Biol Chem. 2019. PMID: 30541921 Free PMC article.
Perspective on Lignin Conversion Strategies That Enable Next Generation Biorefineries.
Shrestha S, Goswami S, Banerjee D, Garcia V, Zhou E, Olmsted CN, Majumder EL, Kumar D, Awasthi D, Mukhopadhyay A, Singer SW, Gladden JM, Simmons BA, Choudhary H. Shrestha S, et al. Among authors: olmsted cn. ChemSusChem. 2024 Aug 26;17(16):e202301460. doi: 10.1002/cssc.202301460. Epub 2024 Apr 26. ChemSusChem. 2024. PMID: 38669480 Review.