Tirmenstein M - Search Results

1

Evaluation of Uracil, Sodium Ascorbate, and Rosiglitazone as Promoters of Urinary Bladder Transitional Cell Carcinomas in Male Sprague-Dawley Rats.

Tirmenstein M, Janovitz E, Dorr T, Song Y, Chen SJ, Granaldi K, Chadwick KD, Mangipudy R, Graziano M, Attalla B, Haile S, Czajkowski M, Foster JR, Bergholm AM, Billger M, Söderberg M. Tirmenstein M, et al. Toxicol Pathol. 2018 Feb;46(2):147-157. doi: 10.1177/0192623318756004. Toxicol Pathol. 2018. PMID: 29471778

2

Utilization of the Zucker Diabetic Fatty (ZDF) Rat Model for Investigating Hypoglycemia-related Toxicities.

Tirmenstein M, Horvath J, Graziano M, Mangipudy R, Dorr T, Colman K, Zinker B, Kirby M, Cheng PT, Patrone L, Kozlosky J, Reilly TP, Wang V, Janovitz E. Tirmenstein M, et al. Toxicol Pathol. 2015 Aug;43(6):825-37. doi: 10.1177/0192623315581020. Epub 2015 Jun 17. Toxicol Pathol. 2015. PMID: 26085543

3

Nonclinical toxicology assessments support the chronic safety of dapagliflozin, a first-in-class sodium-glucose cotransporter 2 inhibitor.

Tirmenstein M, Dorr TE, Janovitz EB, Hagan D, Abell LM, Onorato JM, Whaley JM, Graziano MJ, Reilly TP. Tirmenstein M, et al. Int J Toxicol. 2013 Sep-Oct;32(5):336-50. doi: 10.1177/1091581813505331. Epub 2013 Oct 4. Int J Toxicol. 2013. PMID: 24097127

4

Carcinogenicity risk assessment supports the chronic safety of dapagliflozin, an inhibitor of sodium-glucose co-transporter 2, in the treatment of type 2 diabetes mellitus.

Reilly TP, Graziano MJ, Janovitz EB, Dorr TE, Fairchild C, Lee F, Chen J, Wong T, Whaley JM, Tirmenstein M. Reilly TP, et al. Among authors: tirmenstein m. Diabetes Ther. 2014 Jun;5(1):73-96. doi: 10.1007/s13300-014-0053-3. Epub 2014 Jan 29. Diabetes Ther. 2014. PMID: 24474422 Free PMC article.

5

Serum microRNAs-217 and -375 as biomarkers of acute pancreatic injury in rats.

Calvano J, Edwards G, Hixson C, Burr H, Mangipudy R, Tirmenstein M. Calvano J, et al. Among authors: tirmenstein m. Toxicology. 2016 Aug 10;368-369:1-9. doi: 10.1016/j.tox.2016.08.009. Epub 2016 Aug 10. Toxicology. 2016. PMID: 27521901

6

Evaluation of microRNAs-208 and 133a/b as differential biomarkers of acute cardiac and skeletal muscle toxicity in rats.

Calvano J, Achanzar W, Murphy B, DiPiero J, Hixson C, Parrula C, Burr H, Mangipudy R, Tirmenstein M. Calvano J, et al. Among authors: tirmenstein m. Toxicol Appl Pharmacol. 2016 Dec 1;312:53-60. doi: 10.1016/j.taap.2015.11.015. Epub 2015 Nov 25. Toxicol Appl Pharmacol. 2016. PMID: 26627004

7

Cannabinoid receptor antagonist-induced striated muscle toxicity and ethylmalonic-adipic aciduria in beagle dogs.

Tomlinson L, Tirmenstein MA, Janovitz EB, Aranibar N, Ott KH, Kozlosky JC, Patrone LM, Achanzar WE, Augustine KA, Brannen KC, Carlson KE, Charlap JH, Dubrow KM, Kang L, Rosini LT, Panzica-Kelly JM, Flint OP, Moulin FJ, Megill JR, Zhang H, Bennett MJ, Horvath JJ. Tomlinson L, et al. Among authors: tirmenstein ma. Toxicol Sci. 2012 Oct;129(2):268-79. doi: 10.1093/toxsci/kfs217. Epub 2012 Jul 21. Toxicol Sci. 2012. PMID: 22821849

8

The synthesis of [¹⁴ C]4-acetylphenylalanine, effect on cell viability, and assessment of protein incorporation in male rat hepatocytes.

Maxwell BD, Ly V, Brock B, Dodge R, Tirmenstein M, Calvano J. Maxwell BD, et al. Among authors: tirmenstein m. J Labelled Comp Radiopharm. 2017 Jun 30;60(8):352-356. doi: 10.1002/jlcr.3499. Epub 2017 May 30. J Labelled Comp Radiopharm. 2017. PMID: 28273378

9

Targeting renal glucose reabsorption for the treatment of type 2 diabetes mellitus using the SGLT2 inhibitor dapagliflozin.

Jabbour SA, Whaley JM, Tirmenstein M, Poucher SM, Reilly TP, Boulton DW, Saye J, List JF, Parikh S. Jabbour SA, et al. Among authors: tirmenstein m. Postgrad Med. 2012 Jul;124(4):62-73. doi: 10.3810/pgm.2012.07.2569. Postgrad Med. 2012. PMID: 22913895 Review.

10

Targeting the kidney and glucose excretion with dapagliflozin: preclinical and clinical evidence for SGLT2 inhibition as a new option for treatment of type 2 diabetes mellitus.

Whaley JM, Tirmenstein M, Reilly TP, Poucher SM, Saye J, Parikh S, List JF. Whaley JM, et al. Among authors: tirmenstein m. Diabetes Metab Syndr Obes. 2012;5:135-48. doi: 10.2147/DMSO.S22503. Epub 2012 Jul 23. Diabetes Metab Syndr Obes. 2012. PMID: 22923998 Free PMC article.

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