Werb Z - Search Results

1

Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive basal-like breast cancers.

Takai K, Drain AP, Lawson DA, Littlepage LE, Karpuj M, Kessenbrock K, Le A, Inoue K, Weaver VM, Werb Z. Takai K, et al. Among authors: werb z. Genes Dev. 2018 Feb 1;32(3-4):244-257. doi: 10.1101/gad.301366.117. Epub 2018 Feb 26. Genes Dev. 2018. PMID: 29483153 Free PMC article.

2

GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model.

Kouros-Mehr H, Bechis SK, Slorach EM, Littlepage LE, Egeblad M, Ewald AJ, Pai SY, Ho IC, Werb Z. Kouros-Mehr H, et al. Among authors: werb z. Cancer Cell. 2008 Feb;13(2):141-52. doi: 10.1016/j.ccr.2008.01.011. Cancer Cell. 2008. PMID: 18242514 Free PMC article.

3

A role for matrix metalloproteinases in regulating mammary stem cell function via the Wnt signaling pathway.

Kessenbrock K, Dijkgraaf GJ, Lawson DA, Littlepage LE, Shahi P, Pieper U, Werb Z. Kessenbrock K, et al. Among authors: werb z. Cell Stem Cell. 2013 Sep 5;13(3):300-13. doi: 10.1016/j.stem.2013.06.005. Epub 2013 Jul 18. Cell Stem Cell. 2013. PMID: 23871604 Free PMC article.

4

Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells.

Lawson DA, Bhakta NR, Kessenbrock K, Prummel KD, Yu Y, Takai K, Zhou A, Eyob H, Balakrishnan S, Wang CY, Yaswen P, Goga A, Werb Z. Lawson DA, et al. Among authors: werb z. Nature. 2015 Oct 1;526(7571):131-5. doi: 10.1038/nature15260. Epub 2015 Sep 23. Nature. 2015. PMID: 26416748 Free PMC article.

5

The Cleared Mammary Fat Pad Transplantation Assay for Mammary Epithelial Organogenesis.

Lawson DA, Werb Z, Zong Y, Goldstein AS. Lawson DA, et al. Among authors: werb z. Cold Spring Harb Protoc. 2015 Dec 2;2015(12):pdb.prot078071. doi: 10.1101/pdb.prot078071. Cold Spring Harb Protoc. 2015. PMID: 26631119 Free PMC article.

6

Targeting the cancer-associated fibroblasts as a treatment in triple-negative breast cancer.

Takai K, Le A, Weaver VM, Werb Z. Takai K, et al. Among authors: werb z. Oncotarget. 2016 Dec 13;7(50):82889-82901. doi: 10.18632/oncotarget.12658. Oncotarget. 2016. PMID: 27756881 Free PMC article.

7

Profiling human breast epithelial cells using single cell RNA sequencing identifies cell diversity.

Nguyen QH, Pervolarakis N, Blake K, Ma D, Davis RT, James N, Phung AT, Willey E, Kumar R, Jabart E, Driver I, Rock J, Goga A, Khan SA, Lawson DA, Werb Z, Kessenbrock K. Nguyen QH, et al. Among authors: werb z. Nat Commun. 2018 May 23;9(1):2028. doi: 10.1038/s41467-018-04334-1. Nat Commun. 2018. PMID: 29795293 Free PMC article.

8

Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression.

Maller O, Drain AP, Barrett AS, Borgquist S, Ruffell B, Zakharevich I, Pham TT, Gruosso T, Kuasne H, Lakins JN, Acerbi I, Barnes JM, Nemkov T, Chauhan A, Gruenberg J, Nasir A, Bjarnadottir O, Werb Z, Kabos P, Chen YY, Hwang ES, Park M, Coussens LM, Nelson AC, Hansen KC, Weaver VM. Maller O, et al. Among authors: werb z. Nat Mater. 2021 Apr;20(4):548-559. doi: 10.1038/s41563-020-00849-5. Epub 2020 Nov 30. Nat Mater. 2021. PMID: 33257795 Free PMC article.

9

Matrix metalloproteinases contribute distinct roles in neuroendocrine prostate carcinogenesis, metastasis, and angiogenesis progression.

Littlepage LE, Sternlicht MD, Rougier N, Phillips J, Gallo E, Yu Y, Williams K, Brenot A, Gordon JI, Werb Z. Littlepage LE, et al. Among authors: werb z. Cancer Res. 2010 Mar 15;70(6):2224-34. doi: 10.1158/0008-5472.CAN-09-3515. Epub 2010 Mar 9. Cancer Res. 2010. PMID: 20215503 Free PMC article.

10

The transcription factor ZNF217 is a prognostic biomarker and therapeutic target during breast cancer progression.

Littlepage LE, Adler AS, Kouros-Mehr H, Huang G, Chou J, Krig SR, Griffith OL, Korkola JE, Qu K, Lawson DA, Xue Q, Sternlicht MD, Dijkgraaf GJ, Yaswen P, Rugo HS, Sweeney CA, Collins CC, Gray JW, Chang HY, Werb Z. Littlepage LE, et al. Among authors: werb z. Cancer Discov. 2012 Jul;2(7):638-51. doi: 10.1158/2159-8290.CD-12-0093. Epub 2012 May 10. Cancer Discov. 2012. PMID: 22728437 Free PMC article.

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