Rugg-Gunn PJ - Search Results

1

Molecular profiling of aged neural progenitors identifies Dbx2 as a candidate regulator of age-associated neurogenic decline.

Lupo G, Nisi PS, Esteve P, Paul YL, Novo CL, Sidders B, Khan MA, Biagioni S, Liu HK, Bovolenta P, Cacci E, Rugg-Gunn PJ. Lupo G, et al. Aging Cell. 2018 Jun;17(3):e12745. doi: 10.1111/acel.12745. Epub 2018 Mar 5. Aging Cell. 2018. PMID: 29504228 Free PMC article.

2

The pluripotency factor Nanog regulates pericentromeric heterochromatin organization in mouse embryonic stem cells.

Novo CL, Tang C, Ahmed K, Djuric U, Fussner E, Mullin NP, Morgan NP, Hayre J, Sienerth AR, Elderkin S, Nishinakamura R, Chambers I, Ellis J, Bazett-Jones DP, Rugg-Gunn PJ. Novo CL, et al. Genes Dev. 2016 May 1;30(9):1101-15. doi: 10.1101/gad.275685.115. Epub 2016 Apr 28. Genes Dev. 2016. PMID: 27125671 Free PMC article.

3

Deletion of the Polycomb-Group Protein EZH2 Leads to Compromised Self-Renewal and Differentiation Defects in Human Embryonic Stem Cells.

Collinson A, Collier AJ, Morgan NP, Sienerth AR, Chandra T, Andrews S, Rugg-Gunn PJ. Collinson A, et al. Cell Rep. 2016 Dec 6;17(10):2700-2714. doi: 10.1016/j.celrep.2016.11.032. Cell Rep. 2016. PMID: 27926872 Free PMC article.

4

Transcriptional response of Hoxb genes to retinoid signalling is regionally restricted along the neural tube rostrocaudal axis.

Carucci N, Cacci E, Nisi PS, Licursi V, Paul YL, Biagioni S, Negri R, Rugg-Gunn PJ, Lupo G. Carucci N, et al. R Soc Open Sci. 2017 Apr 5;4(4):160913. doi: 10.1098/rsos.160913. eCollection 2017 Apr. R Soc Open Sci. 2017. PMID: 28484611 Free PMC article.

5

Long-Range Enhancer Interactions Are Prevalent in Mouse Embryonic Stem Cells and Are Reorganized upon Pluripotent State Transition.

Novo CL, Javierre BM, Cairns J, Segonds-Pichon A, Wingett SW, Freire-Pritchett P, Furlan-Magaril M, Schoenfelder S, Fraser P, Rugg-Gunn PJ. Novo CL, et al. Cell Rep. 2018 Mar 6;22(10):2615-2627. doi: 10.1016/j.celrep.2018.02.040. Cell Rep. 2018. PMID: 29514091 Free PMC article.

6

Cell-Surface Proteomics Identifies Differences in Signaling and Adhesion Protein Expression between Naive and Primed Human Pluripotent Stem Cells.

Wojdyla K, Collier AJ, Fabian C, Nisi PS, Biggins L, Oxley D, Rugg-Gunn PJ. Wojdyla K, et al. Stem Cell Reports. 2020 May 12;14(5):972-988. doi: 10.1016/j.stemcr.2020.03.017. Epub 2020 Apr 16. Stem Cell Reports. 2020. PMID: 32302559 Free PMC article.

7

Genome-wide screening identifies Polycomb repressive complex 1.3 as an essential regulator of human naïve pluripotent cell reprogramming.

Collier AJ, Bendall A, Fabian C, Malcolm AA, Tilgner K, Semprich CI, Wojdyla K, Nisi PS, Kishore K, Roamio Franklin VN, Mirshekar-Syahkal B, D'Santos C, Plath K, Yusa K, Rugg-Gunn PJ. Collier AJ, et al. Sci Adv. 2022 Mar 25;8(12):eabk0013. doi: 10.1126/sciadv.abk0013. Epub 2022 Mar 25. Sci Adv. 2022. PMID: 35333572 Free PMC article.

8

Satellite repeat transcripts modulate heterochromatin condensates and safeguard chromosome stability in mouse embryonic stem cells.

Novo CL, Wong EV, Hockings C, Poudel C, Sheekey E, Wiese M, Okkenhaug H, Boulton SJ, Basu S, Walker S, Kaminski Schierle GS, Narlikar GJ, Rugg-Gunn PJ. Novo CL, et al. Among authors: rugg gunn pj. Nat Commun. 2022 Jun 20;13(1):3525. doi: 10.1038/s41467-022-31198-3. Nat Commun. 2022. PMID: 35725842 Free PMC article.

9

Dbx2, an Aging-Related Homeobox Gene, Inhibits the Proliferation of Adult Neural Progenitors.

Giuliani A, Licursi V, Nisi PS, Fiore M, D'Angelo S, Biagioni S, Negri R, Rugg-Gunn PJ, Cacci E, Lupo G. Giuliani A, et al. Among authors: rugg gunn pj. Stem Cell Rev Rep. 2023 Nov;19(8):2837-2851. doi: 10.1007/s12015-023-10600-7. Epub 2023 Aug 22. Stem Cell Rev Rep. 2023. PMID: 37605090 Free PMC article.

10

Comparative Principles of DNA Methylation Reprogramming during Human and Mouse In Vitro Primordial Germ Cell Specification.

von Meyenn F, Berrens RV, Andrews S, Santos F, Collier AJ, Krueger F, Osorno R, Dean W, Rugg-Gunn PJ, Reik W. von Meyenn F, et al. Dev Cell. 2016 Oct 10;39(1):104-115. doi: 10.1016/j.devcel.2016.09.015. Dev Cell. 2016. PMID: 27728778 Free PMC article.

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