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Topoisomerase 1 inhibits MYC promoter activity by inducing G-quadruplex formation.
Keller JG, Hymøller KM, Thorsager ME, Hansen NY, Erlandsen JU, Tesauro C, Simonsen AKW, Andersen AB, Vandsø Petersen K, Holm LL, Stougaard M, Andresen BS, Kristensen P, Frøhlich R, Knudsen BR. Keller JG, et al. Among authors: simonsen akw. Nucleic Acids Res. 2022 Jun 24;50(11):6332-6342. doi: 10.1093/nar/gkac482. Nucleic Acids Res. 2022. PMID: 35687110 Free PMC article.
Detection of the Malaria causing Plasmodium Parasite in Saliva from Infected Patients using Topoisomerase I Activity as a Biomarker.
Hede MS, Fjelstrup S, Lötsch F, Zoleko RM, Klicpera A, Groger M, Mischlinger J, Endame L, Veletzky L, Neher R, Simonsen AKW, Petersen E, Mombo-Ngoma G, Stougaard M, Ho YP, Labouriau R, Ramharter M, Knudsen BR. Hede MS, et al. Among authors: simonsen akw. Sci Rep. 2018 Mar 7;8(1):4122. doi: 10.1038/s41598-018-22378-7. Sci Rep. 2018. PMID: 29515150 Free PMC article.