Hackel BJ - Search Results

1

Engineering Reversible Cell-Cell Interactions with Lipid Anchored Prosthetic Receptors.

Csizmar CM, Petersburg JR, Hendricks A, Stern LA, Hackel BJ, Wagner CR. Csizmar CM, et al. Among authors: hackel bj. Bioconjug Chem. 2018 Apr 18;29(4):1291-1301. doi: 10.1021/acs.bioconjchem.8b00058. Epub 2018 Mar 23. Bioconjug Chem. 2018. PMID: 29537253 Free PMC article.

2

Titratable Avidity Reduction Enhances Affinity Discrimination in Mammalian Cellular Selections of Yeast-Displayed Ligands.

Stern LA, Csizmar CM, Woldring DR, Wagner CR, Hackel BJ. Stern LA, et al. Among authors: hackel bj. ACS Comb Sci. 2017 May 8;19(5):315-323. doi: 10.1021/acscombsci.6b00191. Epub 2017 Mar 31. ACS Comb Sci. 2017. PMID: 28322543 Free PMC article.

3

Multivalent Ligand Binding to Cell Membrane Antigens: Defining the Interplay of Affinity, Valency, and Expression Density.

Csizmar CM, Petersburg JR, Perry TJ, Rozumalski L, Hackel BJ, Wagner CR. Csizmar CM, et al. Among authors: hackel bj. J Am Chem Soc. 2019 Jan 9;141(1):251-261. doi: 10.1021/jacs.8b09198. Epub 2018 Dec 17. J Am Chem Soc. 2019. PMID: 30507196 Free PMC article.

4

Ligand Engineering via Yeast Surface Display and Adherent Cell Panning.

Stern LA, Lown PS, Hackel BJ. Stern LA, et al. Among authors: hackel bj. Methods Mol Biol. 2020;2070:303-320. doi: 10.1007/978-1-4939-9853-1_17. Methods Mol Biol. 2020. PMID: 31625103 Free PMC article.

5

Cellular-Based Selections Aid Yeast-Display Discovery of Genuine Cell-Binding Ligands: Targeting Oncology Vascular Biomarker CD276.

Stern LA, Lown PS, Kobe AC, Abou-Elkacem L, Willmann JK, Hackel BJ. Stern LA, et al. Among authors: hackel bj. ACS Comb Sci. 2019 Mar 11;21(3):207-222. doi: 10.1021/acscombsci.8b00156. Epub 2019 Jan 24. ACS Comb Sci. 2019. PMID: 30620189 Free PMC article.

6

Geometry and expression enhance enrichment of functional yeast-displayed ligands via cell panning.

Stern LA, Schrack IA, Johnson SM, Deshpande A, Bennett NR, Harasymiw LA, Gardner MK, Hackel BJ. Stern LA, et al. Among authors: hackel bj. Biotechnol Bioeng. 2016 Nov;113(11):2328-41. doi: 10.1002/bit.26001. Epub 2016 Jun 30. Biotechnol Bioeng. 2016. PMID: 27144954 Free PMC article.

7

Alternative Non-Antibody Protein Scaffolds for Molecular Imaging of Cancer.

Stern LA, Case BA, Hackel BJ. Stern LA, et al. Among authors: hackel bj. Curr Opin Chem Eng. 2013 Nov;2(4):10.1016/j.coche.2013.08.009. doi: 10.1016/j.coche.2013.08.009. Curr Opin Chem Eng. 2013. PMID: 24358455 Free PMC article.

8

A Gradient of Sitewise Diversity Promotes Evolutionary Fitness for Binder Discovery in a Three-Helix Bundle Protein Scaffold.

Woldring DR, Holec PV, Stern LA, Du Y, Hackel BJ. Woldring DR, et al. Among authors: hackel bj. Biochemistry. 2017 Mar 21;56(11):1656-1671. doi: 10.1021/acs.biochem.6b01142. Epub 2017 Mar 9. Biochemistry. 2017. PMID: 28248518 Free PMC article.

9

Evaluation of affibody charge modification identified by synthetic consensus design in molecular PET imaging of epidermal growth factor receptor.

Case BA, Kruziki MA, Stern LA, Hackel BJ. Case BA, et al. Among authors: hackel bj. Mol Syst Des Eng. 2018 Feb 28;3(1):171-182. doi: 10.1039/C7ME00095B. Epub 2017 Nov 9. Mol Syst Des Eng. 2018. PMID: 31467687 Free PMC article.

10

Efficacy of Affibody-Based Ultrasound Molecular Imaging of Vascular B7-H3 for Breast Cancer Detection.

Bam R, Lown PS, Stern LA, Sharma K, Wilson KE, Bean GR, Lutz AM, Paulmurugan R, Hackel BJ, Dahl J, Abou-Elkacem L. Bam R, et al. Among authors: hackel bj. Clin Cancer Res. 2020 May 1;26(9):2140-2150. doi: 10.1158/1078-0432.CCR-19-1655. Epub 2020 Jan 10. Clin Cancer Res. 2020. PMID: 31924738 Free PMC article.

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