Shakkottai VG - Search Results

1

Targeting potassium channels to treat cerebellar ataxia.

Bushart DD, Chopra R, Singh V, Murphy GG, Wulff H, Shakkottai VG. Bushart DD, et al. Among authors: shakkottai vg. Ann Clin Transl Neurol. 2018 Jan 22;5(3):297-314. doi: 10.1002/acn3.527. eCollection 2018 Mar. Ann Clin Transl Neurol. 2018. PMID: 29560375 Free PMC article.

2

SCAview: an Intuitive Visual Approach to the Integrative Analysis of Clinical Data in Spinocerebellar Ataxias.

Uebachs M, Wegner P, Schaaf S, Kugai S, Jacobi H, Kuo SH, Ashizawa T, Fluck J; EUROSCA study group; ESMI study group; RISCA study group; CRC-SCA study group; SCA Registry study group; Klockgether T, Faber J. Uebachs M, et al. Cerebellum. 2024 Jun;23(3):887-895. doi: 10.1007/s12311-023-01546-0. Epub 2023 Mar 31. Cerebellum. 2024. PMID: 37002505 Free PMC article.

3

Modulators of small- and intermediate-conductance calcium-activated potassium channels and their therapeutic indications.

Wulff H, Kolski-Andreaco A, Sankaranarayanan A, Sabatier JM, Shakkottai V. Wulff H, et al. Curr Med Chem. 2007;14(13):1437-57. doi: 10.2174/092986707780831186. Curr Med Chem. 2007. PMID: 17584055 Review.

4

Early changes in cerebellar physiology accompany motor dysfunction in the polyglutamine disease spinocerebellar ataxia type 3.

Shakkottai VG, do Carmo Costa M, Dell'Orco JM, Sankaranarayanan A, Wulff H, Paulson HL. Shakkottai VG, et al. J Neurosci. 2011 Sep 7;31(36):13002-14. doi: 10.1523/JNEUROSCI.2789-11.2011. J Neurosci. 2011. PMID: 21900579 Free PMC article.

5

Alterations in cerebellar physiology are associated with a stiff-legged gait in Atcay(ji-hes) mice.

Luna-Cancalon K, Sikora KM, Pappas SS, Singh V, Wulff H, Paulson HL, Burmeister M, Shakkottai VG. Luna-Cancalon K, et al. Among authors: shakkottai vg. Neurobiol Dis. 2014 Jul;67:140-8. doi: 10.1016/j.nbd.2014.03.020. Epub 2014 Apr 12. Neurobiol Dis. 2014. PMID: 24727095 Free PMC article.

6

The role for alterations in neuronal activity in the pathogenesis of polyglutamine repeat disorders.

Chopra R, Shakkottai VG. Chopra R, et al. Among authors: shakkottai vg. Neurotherapeutics. 2014 Oct;11(4):751-63. doi: 10.1007/s13311-014-0289-7. Neurotherapeutics. 2014. PMID: 24986674 Free PMC article. Review.

7

Translating cerebellar Purkinje neuron physiology to progress in dominantly inherited ataxia.

Chopra R, Shakkottai VG. Chopra R, et al. Among authors: shakkottai vg. Future Neurol. 2014 Mar 1;9(2):187-196. doi: 10.2217/fnl.14.6. Future Neurol. 2014. PMID: 25221437 Free PMC article.

8

Neuronal Atrophy Early in Degenerative Ataxia Is a Compensatory Mechanism to Regulate Membrane Excitability.

Dell'Orco JM, Wasserman AH, Chopra R, Ingram MA, Hu YS, Singh V, Wulff H, Opal P, Orr HT, Shakkottai VG. Dell'Orco JM, et al. Among authors: shakkottai vg. J Neurosci. 2015 Aug 12;35(32):11292-307. doi: 10.1523/JNEUROSCI.1357-15.2015. J Neurosci. 2015. PMID: 26269637 Free PMC article.

9

Single amino acid deletion in transmembrane segment D4S6 of sodium channel Scn8a (Nav1.6) in a mouse mutant with a chronic movement disorder.

Jones JM, Dionne L, Dell'Orco J, Parent R, Krueger JN, Cheng X, Dib-Hajj SD, Bunton-Stasyshyn RK, Sharkey LM, Dowling JJ, Murphy GG, Shakkottai VG, Shrager P, Meisler MH. Jones JM, et al. Among authors: shakkottai vg. Neurobiol Dis. 2016 May;89:36-45. doi: 10.1016/j.nbd.2016.01.018. Epub 2016 Jan 22. Neurobiol Dis. 2016. PMID: 26807988 Free PMC article.

10

Precision medicine in spinocerebellar ataxias: treatment based on common mechanisms of disease.

Bushart DD, Murphy GG, Shakkottai VG. Bushart DD, et al. Among authors: shakkottai vg. Ann Transl Med. 2016 Jan;4(2):25. doi: 10.3978/j.issn.2305-5839.2016.01.06. Ann Transl Med. 2016. PMID: 26889478 Free PMC article. Review.

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