Misawa H - Search Results

1

Innate immune adaptor TRIF deficiency accelerates disease progression of ALS mice with accumulation of aberrantly activated astrocytes.

Komine O, Yamashita H, Fujimori-Tonou N, Koike M, Jin S, Moriwaki Y, Endo F, Watanabe S, Uematsu S, Akira S, Uchiyama Y, Takahashi R, Misawa H, Yamanaka K. Komine O, et al. Among authors: misawa h. Cell Death Differ. 2018 Dec;25(12):2130-2146. doi: 10.1038/s41418-018-0098-3. Epub 2018 Mar 22. Cell Death Differ. 2018. PMID: 29568058 Free PMC article.

2

Neuregulin 1 confers neuroprotection in SOD1-linked amyotrophic lateral sclerosis mice via restoration of C-boutons of spinal motor neurons.

Lasiene J, Komine O, Fujimori-Tonou N, Powers B, Endo F, Watanabe S, Shijie J, Ravits J, Horner P, Misawa H, Yamanaka K. Lasiene J, et al. Among authors: misawa h. Acta Neuropathol Commun. 2016 Feb 18;4:15. doi: 10.1186/s40478-016-0286-7. Acta Neuropathol Commun. 2016. PMID: 26891847 Free PMC article.

3

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis.

Yamanaka K, Chun SJ, Boillee S, Fujimori-Tonou N, Yamashita H, Gutmann DH, Takahashi R, Misawa H, Cleveland DW. Yamanaka K, et al. Among authors: misawa h. Nat Neurosci. 2008 Mar;11(3):251-3. doi: 10.1038/nn2047. Epub 2008 Feb 3. Nat Neurosci. 2008. PMID: 18246065 Free PMC article.

4

Motor neuron-specific disruption of proteasomes, but not autophagy, replicates amyotrophic lateral sclerosis.

Tashiro Y, Urushitani M, Inoue H, Koike M, Uchiyama Y, Komatsu M, Tanaka K, Yamazaki M, Abe M, Misawa H, Sakimura K, Ito H, Takahashi R. Tashiro Y, et al. Among authors: misawa h. J Biol Chem. 2012 Dec 14;287(51):42984-94. doi: 10.1074/jbc.M112.417600. Epub 2012 Oct 24. J Biol Chem. 2012. PMID: 23095749 Free PMC article.

5

Loss of TDP-43 causes age-dependent progressive motor neuron degeneration.

Iguchi Y, Katsuno M, Niwa J, Takagi S, Ishigaki S, Ikenaka K, Kawai K, Watanabe H, Yamanaka K, Takahashi R, Misawa H, Sasaki S, Tanaka F, Sobue G. Iguchi Y, et al. Among authors: misawa h. Brain. 2013 May;136(Pt 5):1371-82. doi: 10.1093/brain/awt029. Epub 2013 Feb 28. Brain. 2013. PMID: 23449777

6

SIRT1 overexpression ameliorates a mouse model of SOD1-linked amyotrophic lateral sclerosis via HSF1/HSP70i chaperone system.

Watanabe S, Ageta-Ishihara N, Nagatsu S, Takao K, Komine O, Endo F, Miyakawa T, Misawa H, Takahashi R, Kinoshita M, Yamanaka K. Watanabe S, et al. Among authors: misawa h. Mol Brain. 2014 Aug 29;7:62. doi: 10.1186/s13041-014-0062-1. Mol Brain. 2014. PMID: 25167838 Free PMC article.

7

A misfolded dimer of Cu/Zn-superoxide dismutase leading to pathological oligomerization in amyotrophic lateral sclerosis.

Anzai I, Tokuda E, Mukaiyama A, Akiyama S, Endo F, Yamanaka K, Misawa H, Furukawa Y. Anzai I, et al. Among authors: misawa h. Protein Sci. 2017 Mar;26(3):484-496. doi: 10.1002/pro.3094. Epub 2017 Feb 12. Protein Sci. 2017. PMID: 27977888 Free PMC article.

8

Dissociation of blood-brain barrier disruption and disease manifestation in an aquaporin-4-deficient mouse model of amyotrophic lateral sclerosis.

Watanabe-Matsumoto S, Moriwaki Y, Okuda T, Ohara S, Yamanaka K, Abe Y, Yasui M, Misawa H. Watanabe-Matsumoto S, et al. Among authors: misawa h. Neurosci Res. 2018 Aug;133:48-57. doi: 10.1016/j.neures.2017.11.001. Epub 2017 Nov 15. Neurosci Res. 2018. PMID: 29154923

9

A copper-deficient form of mutant Cu/Zn-superoxide dismutase as an early pathological species in amyotrophic lateral sclerosis.

Tokuda E, Nomura T, Ohara S, Watanabe S, Yamanaka K, Morisaki Y, Misawa H, Furukawa Y. Tokuda E, et al. Among authors: misawa h. Biochim Biophys Acta Mol Basis Dis. 2018 Jun;1864(6 Pt A):2119-2130. doi: 10.1016/j.bbadis.2018.03.015. Epub 2018 Mar 16. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 29551730 Free article.

10

Immunochemical characterization on pathological oligomers of mutant Cu/Zn-superoxide dismutase in amyotrophic lateral sclerosis.

Tokuda E, Anzai I, Nomura T, Toichi K, Watanabe M, Ohara S, Watanabe S, Yamanaka K, Morisaki Y, Misawa H, Furukawa Y. Tokuda E, et al. Among authors: misawa h. Mol Neurodegener. 2017 Jan 5;12(1):2. doi: 10.1186/s13024-016-0145-9. Mol Neurodegener. 2017. PMID: 28057013 Free PMC article.

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