Watanabe S - Search Results

1

Innate immune adaptor TRIF deficiency accelerates disease progression of ALS mice with accumulation of aberrantly activated astrocytes.

Komine O, Yamashita H, Fujimori-Tonou N, Koike M, Jin S, Moriwaki Y, Endo F, Watanabe S, Uematsu S, Akira S, Uchiyama Y, Takahashi R, Misawa H, Yamanaka K. Komine O, et al. Among authors: watanabe s. Cell Death Differ. 2018 Dec;25(12):2130-2146. doi: 10.1038/s41418-018-0098-3. Epub 2018 Mar 22. Cell Death Differ. 2018. PMID: 29568058 Free PMC article.

2

Disease causing mutants of TDP-43 nucleic acid binding domains are resistant to aggregation and have increased stability and half-life.

Austin JA, Wright GS, Watanabe S, Grossmann JG, Antonyuk SV, Yamanaka K, Hasnain SS. Austin JA, et al. Among authors: watanabe s. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4309-14. doi: 10.1073/pnas.1317317111. Epub 2014 Mar 3. Proc Natl Acad Sci U S A. 2014. PMID: 24591609 Free PMC article.

3

SIRT1 overexpression ameliorates a mouse model of SOD1-linked amyotrophic lateral sclerosis via HSF1/HSP70i chaperone system.

Watanabe S, Ageta-Ishihara N, Nagatsu S, Takao K, Komine O, Endo F, Miyakawa T, Misawa H, Takahashi R, Kinoshita M, Yamanaka K. Watanabe S, et al. Mol Brain. 2014 Aug 29;7:62. doi: 10.1186/s13041-014-0062-1. Mol Brain. 2014. PMID: 25167838 Free PMC article.

4

Astrocyte-derived TGF-β1 accelerates disease progression in ALS mice by interfering with the neuroprotective functions of microglia and T cells.

Endo F, Komine O, Fujimori-Tonou N, Katsuno M, Jin S, Watanabe S, Sobue G, Dezawa M, Wyss-Coray T, Yamanaka K. Endo F, et al. Among authors: watanabe s. Cell Rep. 2015 Apr 28;11(4):592-604. doi: 10.1016/j.celrep.2015.03.053. Epub 2015 Apr 16. Cell Rep. 2015. PMID: 25892237 Free article.

5

Mahogunin ring finger 1 confers cytoprotection against mutant SOD1 aggresomes and is defective in an ALS mouse model.

Chhangani D, Endo F, Amanullah A, Upadhyay A, Watanabe S, Mishra R, Yamanaka K, Mishra A. Chhangani D, et al. Among authors: watanabe s. Neurobiol Dis. 2016 Feb;86:16-28. doi: 10.1016/j.nbd.2015.11.017. Epub 2015 Nov 29. Neurobiol Dis. 2016. PMID: 26607786

6

Neuregulin 1 confers neuroprotection in SOD1-linked amyotrophic lateral sclerosis mice via restoration of C-boutons of spinal motor neurons.

Lasiene J, Komine O, Fujimori-Tonou N, Powers B, Endo F, Watanabe S, Shijie J, Ravits J, Horner P, Misawa H, Yamanaka K. Lasiene J, et al. Among authors: watanabe s. Acta Neuropathol Commun. 2016 Feb 18;4:15. doi: 10.1186/s40478-016-0286-7. Acta Neuropathol Commun. 2016. PMID: 26891847 Free PMC article.

7

Mitochondria-associated membrane collapse is a common pathomechanism in SIGMAR1- and SOD1-linked ALS.

Watanabe S, Ilieva H, Tamada H, Nomura H, Komine O, Endo F, Jin S, Mancias P, Kiyama H, Yamanaka K. Watanabe S, et al. EMBO Mol Med. 2016 Dec 1;8(12):1421-1437. doi: 10.15252/emmm.201606403. Print 2016 Dec. EMBO Mol Med. 2016. PMID: 27821430 Free PMC article.

8

Immunochemical characterization on pathological oligomers of mutant Cu/Zn-superoxide dismutase in amyotrophic lateral sclerosis.

Tokuda E, Anzai I, Nomura T, Toichi K, Watanabe M, Ohara S, Watanabe S, Yamanaka K, Morisaki Y, Misawa H, Furukawa Y. Tokuda E, et al. Among authors: watanabe s, watanabe m. Mol Neurodegener. 2017 Jan 5;12(1):2. doi: 10.1186/s13024-016-0145-9. Mol Neurodegener. 2017. PMID: 28057013 Free PMC article.

9

TDP-43 accelerates age-dependent degeneration of interneurons.

Tsuiji H, Inoue I, Takeuchi M, Furuya A, Yamakage Y, Watanabe S, Koike M, Hattori M, Yamanaka K. Tsuiji H, et al. Among authors: watanabe s. Sci Rep. 2017 Nov 2;7(1):14972. doi: 10.1038/s41598-017-14966-w. Sci Rep. 2017. PMID: 29097807 Free PMC article.

10

Intracerebroventricular administration of Cystatin C ameliorates disease in SOD1-linked amyotrophic lateral sclerosis mice.

Watanabe S, Komine O, Endo F, Wakasugi K, Yamanaka K. Watanabe S, et al. J Neurochem. 2018 Apr;145(1):80-89. doi: 10.1111/jnc.14285. Epub 2018 Feb 7. J Neurochem. 2018. PMID: 29282717 Free PMC article.

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