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Type III CRISPR-Cas complexes act as protein-assisted ribozymes during target RNA cleavage.
Schwartz EA, Bravo JPK, Ahsan M, Macias LA, McCafferty CL, Dangerfield TL, Walker JN, Brodbelt JS, Palermo G, Fineran PC, Fagerlund RD, Taylor DW. Schwartz EA, et al. Among authors: fineran pc. Res Sq [Preprint]. 2023 Apr 27:rs.3.rs-2837968. doi: 10.21203/rs.3.rs-2837968/v1. Res Sq. 2023. Update in: Nat Commun. 2024 Apr 18;15(1):3324. doi: 10.1038/s41467-024-47506-y. PMID: 37163044 Free PMC article. Updated. Preprint.
CasPEDIA Database: a functional classification system for class 2 CRISPR-Cas enzymes.
Adler BA, Trinidad MI, Bellieny-Rabelo D, Zhang E, Karp HM, Skopintsev P, Thornton BW, Weissman RF, Yoon PH, Chen L, Hessler T, Eggers AR, Colognori D, Boger R, Doherty EE, Tsuchida CA, Tran RV, Hofman L, Shi H, Wasko KM, Zhou Z, Xia C, Al-Shimary MJ, Patel JR, Thomas VCJX, Pattali R, Kan MJ, Vardapetyan A, Yang A, Lahiri A, Maxwell MF, Murdock AG, Ramit GC, Henderson HR, Calvert RW, Bamert RS, Knott GJ, Lapinaite A, Pausch P, Cofsky JC, Sontheimer EJ, Wiedenheft B, Fineran PC, Brouns SJJ, Sashital DG, Thomas BC, Brown CT, Goltsman DSA, Barrangou R, Siksnys V, Banfield JF, Savage DF, Doudna JA. Adler BA, et al. Among authors: fineran pc. Nucleic Acids Res. 2024 Jan 5;52(D1):D590-D596. doi: 10.1093/nar/gkad890. Nucleic Acids Res. 2024. PMID: 37889041 Free PMC article.
Bacteriophages suppress CRISPR-Cas immunity using RNA-based anti-CRISPRs.
Camara-Wilpert S, Mayo-Muñoz D, Russel J, Fagerlund RD, Madsen JS, Fineran PC, Sørensen SJ, Pinilla-Redondo R. Camara-Wilpert S, et al. Among authors: fineran pc. Nature. 2023 Nov;623(7987):601-607. doi: 10.1038/s41586-023-06612-5. Epub 2023 Oct 18. Nature. 2023. PMID: 37853129 Free PMC article.
RNA targeting and cleavage by the type III-Dv CRISPR effector complex.
Schwartz EA, Bravo JPK, Ahsan M, Macias LA, McCafferty CL, Dangerfield TL, Walker JN, Brodbelt JS, Palermo G, Fineran PC, Fagerlund RD, Taylor DW. Schwartz EA, et al. Among authors: fineran pc. Nat Commun. 2024 Apr 18;15(1):3324. doi: 10.1038/s41467-024-47506-y. Nat Commun. 2024. PMID: 38637512 Free PMC article.
An OmpW-dependent T4-like phage infects Serratia sp. ATCC 39006.
Mahler M, Malone LM, van den Berg DF, Smith LM, Brouns SJJ, Fineran PC. Mahler M, et al. Among authors: fineran pc. Microb Genom. 2023 Mar;9(3):mgen000968. doi: 10.1099/mgen.0.000968. Microb Genom. 2023. PMID: 36995210 Free PMC article.
134 results