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Dectin-1/2-induced autocrine PGE2 signaling licenses dendritic cells to prime Th2 responses.
Kaisar MMM, Ritter M, Del Fresno C, Jónasdóttir HS, van der Ham AJ, Pelgrom LR, Schramm G, Layland LE, Sancho D, Prazeres da Costa C, Giera M, Yazdanbakhsh M, Everts B. Kaisar MMM, et al. Among authors: schramm g. PLoS Biol. 2018 Apr 18;16(4):e2005504. doi: 10.1371/journal.pbio.2005504. eCollection 2018 Apr. PLoS Biol. 2018. PMID: 29668708 Free PMC article.
Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses.
Everts B, Perona-Wright G, Smits HH, Hokke CH, van der Ham AJ, Fitzsimmons CM, Doenhoff MJ, van der Bosch J, Mohrs K, Haas H, Mohrs M, Yazdanbakhsh M, Schramm G. Everts B, et al. Among authors: schramm g. J Exp Med. 2009 Aug 3;206(8):1673-80. doi: 10.1084/jem.20082460. Epub 2009 Jul 27. J Exp Med. 2009. PMID: 19635864 Free PMC article.
Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor.
Everts B, Hussaarts L, Driessen NN, Meevissen MH, Schramm G, van der Ham AJ, van der Hoeven B, Scholzen T, Burgdorf S, Mohrs M, Pearce EJ, Hokke CH, Haas H, Smits HH, Yazdanbakhsh M. Everts B, et al. Among authors: schramm g. J Exp Med. 2012 Sep 24;209(10):1753-67, S1. doi: 10.1084/jem.20111381. Epub 2012 Sep 10. J Exp Med. 2012. PMID: 22966004 Free PMC article.
Drug-induced exposure of Schistosoma mansoni antigens SmCD59a and SmKK7.
Reimers N, Homann A, Höschler B, Langhans K, Wilson RA, Pierrot C, Khalife J, Grevelding CG, Chalmers IW, Yazdanbakhsh M, Hoffmann KF, Hokke CH, Haas H, Schramm G. Reimers N, et al. Among authors: schramm g. PLoS Negl Trop Dis. 2015 Mar 16;9(3):e0003593. doi: 10.1371/journal.pntd.0003593. eCollection 2015 Mar. PLoS Negl Trop Dis. 2015. PMID: 25774883 Free PMC article.
Production and glyco-engineering of immunomodulatory helminth glycoproteins in plants.
Wilbers RH, Westerhof LB, van Noort K, Obieglo K, Driessen NN, Everts B, Gringhuis SI, Schramm G, Goverse A, Smant G, Bakker J, Smits HH, Yazdanbakhsh M, Schots A, Hokke CH. Wilbers RH, et al. Among authors: schramm g. Sci Rep. 2017 Apr 10;7:45910. doi: 10.1038/srep45910. Sci Rep. 2017. PMID: 28393916 Free PMC article.
High-mannose glycans from Schistosoma mansoni eggs are important for priming of Th2 responses via Dectin-2 and prostaglandin E2.
Almeida L, van Roey R, Patente TA, Otto F, Veldhuizen T, Ghorasaini M, van Diepen A, Schramm G, Liu J, Idborg H, Korotkova M, Jakobsson PJ, Giera M, Hokke CH, Everts B. Almeida L, et al. Among authors: schramm g. Front Immunol. 2024 Apr 29;15:1372927. doi: 10.3389/fimmu.2024.1372927. eCollection 2024. Front Immunol. 2024. PMID: 38742105 Free PMC article.
314 results