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Mutant APC reshapes Wnt signaling plasma membrane nanodomains by altering cholesterol levels via oncogenic β-catenin.
Erazo-Oliveras A, Muñoz-Vega M, Mlih M, Thiriveedi V, Salinas ML, Rivera-Rodríguez JM, Kim E, Wright RC, Wang X, Landrock KK, Goldsby JS, Mullens DA, Roper J, Karpac J, Chapkin RS. Erazo-Oliveras A, et al. Among authors: mlih m. Nat Commun. 2023 Jul 19;14(1):4342. doi: 10.1038/s41467-023-39640-w. Nat Commun. 2023. PMID: 37468468 Free PMC article.
Convergent Signaling Pathways Controlled by LRP1 (Receptor-related Protein 1) Cytoplasmic and Extracellular Domains Limit Cellular Cholesterol Accumulation.
El Asmar Z, Terrand J, Jenty M, Host L, Mlih M, Zerr A, Justiniano H, Matz RL, Boudier C, Scholler E, Garnier JM, Bertaccini D, Thiersé D, Schaeffer C, Van Dorsselaer A, Herz J, Bruban V, Boucher P. El Asmar Z, et al. Among authors: mlih m. J Biol Chem. 2016 Mar 4;291(10):5116-27. doi: 10.1074/jbc.M116.714485. Epub 2016 Jan 19. J Biol Chem. 2016. PMID: 26792864 Free PMC article.
The nuclear hormone receptor PPARγ counteracts vascular calcification by inhibiting Wnt5a signalling in vascular smooth muscle cells.
Woldt E, Terrand J, Mlih M, Matz RL, Bruban V, Coudane F, Foppolo S, El Asmar Z, Chollet ME, Ninio E, Bednarczyk A, Thiersé D, Schaeffer C, Van Dorsselaer A, Boudier C, Wahli W, Chambon P, Metzger D, Herz J, Boucher P. Woldt E, et al. Among authors: mlih m. Nat Commun. 2012;3:1077. doi: 10.1038/ncomms2087. Nat Commun. 2012. PMID: 23011131 Free PMC article.
The Src homology and collagen A (ShcA) adaptor protein is required for the spatial organization of the costamere/Z-disk network during heart development.
Mlih M, Host L, Martin S, Niederhoffer N, Monassier L, Terrand J, Messaddeq N, Radke M, Gotthardt M, Bruban V, Kober F, Bernard M, Canet-Soulas E, Abt-Jijon F, Boucher P, Matz RL. Mlih M, et al. J Biol Chem. 2015 Jan 23;290(4):2419-30. doi: 10.1074/jbc.M114.597377. Epub 2014 Dec 8. J Biol Chem. 2015. PMID: 25488665 Free PMC article.
15 results