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A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer's disease.
Mostafavi S, Gaiteri C, Sullivan SE, White CC, Tasaki S, Xu J, Taga M, Klein HU, Patrick E, Komashko V, McCabe C, Smith R, Bradshaw EM, Root DE, Regev A, Yu L, Chibnik LB, Schneider JA, Young-Pearse TL, Bennett DA, De Jager PL. Mostafavi S, et al. Among authors: klein hu. Nat Neurosci. 2018 Jun;21(6):811-819. doi: 10.1038/s41593-018-0154-9. Epub 2018 May 25. Nat Neurosci. 2018. PMID: 29802388 Free PMC article.
Rheumatoid arthritis-associated RBPJ polymorphism alters memory CD4+ T cells.
Orent W, Mchenry AR, Rao DA, White C, Klein HU, Bassil R, Srivastava G, Replogle JM, Raj T, Frangieh M, Cimpean M, Cuerdon N, Chibnik L, Khoury SJ, Karlson EW, Brenner MB, De Jager P, Bradshaw EM, Elyaman W. Orent W, et al. Among authors: klein hu. Hum Mol Genet. 2016 Jan 15;25(2):404-17. doi: 10.1093/hmg/ddv474. Epub 2015 Nov 24. Hum Mol Genet. 2016. PMID: 26604133 Free PMC article.
Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data.
White CC, Yang HS, Yu L, Chibnik LB, Dawe RJ, Yang J, Klein HU, Felsky D, Ramos-Miguel A, Arfanakis K, Honer WG, Sperling RA, Schneider JA, Bennett DA, De Jager PL. White CC, et al. Among authors: klein hu. PLoS Med. 2017 Apr 25;14(4):e1002287. doi: 10.1371/journal.pmed.1002287. eCollection 2017 Apr. PLoS Med. 2017. PMID: 28441426 Free PMC article.
UNC5C variants are associated with cerebral amyloid angiopathy.
Yang HS, White CC, Chibnik LB, Klein HU, Schneider JA, Bennett DA, De Jager PL. Yang HS, et al. Among authors: klein hu. Neurol Genet. 2017 Jul 18;3(4):e176. doi: 10.1212/NXG.0000000000000176. eCollection 2017 Aug. Neurol Genet. 2017. PMID: 28761931 Free PMC article.
MS AHI1 genetic risk promotes IFNγ+ CD4+ T cells.
Kaskow BJ, Buttrick TS, Klein HU, White C, Bourgeois JR, Ferland RJ, Patsopoulos N, Bradshaw EM, De Jager PL, Elyaman W. Kaskow BJ, et al. Among authors: klein hu. Neurol Neuroimmunol Neuroinflamm. 2017 Dec 8;5(1):e414. doi: 10.1212/NXI.0000000000000414. eCollection 2018 Jan. Neurol Neuroimmunol Neuroinflamm. 2017. PMID: 29379820 Free PMC article.
How do we measure the epigenome(s)?
Klein HU, De Jager PL. Klein HU, et al. Mult Scler. 2018 Apr;24(4):446-448. doi: 10.1177/1352458517750772. Mult Scler. 2018. PMID: 29722595 Review. No abstract available.
253 results