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FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells.
Basu S, Needham LM, Lando D, Taylor EJR, Wohlfahrt KJ, Shah D, Boucher W, Tan YL, Bates LE, Tkachenko O, Cramard J, Lagerholm BC, Eggeling C, Hendrich B, Klenerman D, Lee SF, Laue ED. Basu S, et al. Among authors: lagerholm bc. Nat Commun. 2018 Jun 28;9(1):2520. doi: 10.1038/s41467-018-04486-0. Nat Commun. 2018. PMID: 29955052 Free PMC article.
Cytoskeletal actin dynamics shape a ramifying actin network underpinning immunological synapse formation.
Fritzsche M, Fernandes RA, Chang VT, Colin-York H, Clausen MP, Felce JH, Galiani S, Erlenkämper C, Santos AM, Heddleston JM, Pedroza-Pacheco I, Waithe D, de la Serna JB, Lagerholm BC, Liu TL, Chew TL, Betzig E, Davis SJ, Eggeling C. Fritzsche M, et al. Among authors: lagerholm bc. Sci Adv. 2017 Jun 21;3(6):e1603032. doi: 10.1126/sciadv.1603032. eCollection 2017 Jun. Sci Adv. 2017. PMID: 28691087 Free PMC article.
A cell topography-based mechanism for ligand discrimination by the T cell receptor.
Fernandes RA, Ganzinger KA, Tzou JC, Jönsson P, Lee SF, Palayret M, Santos AM, Carr AR, Ponjavic A, Chang VT, Macleod C, Lagerholm BC, Lindsay AE, Dushek O, Tilevik A, Davis SJ, Klenerman D. Fernandes RA, et al. Among authors: lagerholm bc. Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):14002-14010. doi: 10.1073/pnas.1817255116. Epub 2019 Jun 20. Proc Natl Acad Sci U S A. 2019. PMID: 31221762 Free PMC article.
44 results