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Complement C3a and C5a receptors promote GVHD by suppressing mitophagy in recipient dendritic cells.
Nguyen H, Kuril S, Bastian D, Kim J, Zhang M, Vaena SG, Dany M, Dai M, Heinrichs JL, Daenthanasanmak A, Iamsawat S, Schutt S, Fu J, Wu Y, Fairlie DP, Atkinson C, Ogretmen B, Tomlinson S, Yu XZ. Nguyen H, et al. Among authors: zhang m. JCI Insight. 2018 Dec 20;3(24):e121697. doi: 10.1172/jci.insight.121697. JCI Insight. 2018. PMID: 30568037 Free PMC article.
Targeting the Complement Alternative Pathway Permits Graft Versus Leukemia Activity while Preventing Graft Versus Host Disease.
Nguyen H, Alawieh A, Bastian D, Kuril S, Dai M, Daenthanasanmak A, Zhang M, Iamsawat S, Schutt SD, Wu Y, Sleiman MM, Shetty A, Atkinson C, Sun S, Varela JC, Tomlinson S, Yu XZ. Nguyen H, et al. Among authors: zhang m. Clin Cancer Res. 2020 Jul 1;26(13):3481-3490. doi: 10.1158/1078-0432.CCR-19-1717. Epub 2020 Jan 9. Clin Cancer Res. 2020. PMID: 31919135 Free PMC article.
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