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168 results

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Page 1
Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD.
Garcia D, Hellberg K, Chaix A, Wallace M, Herzig S, Badur MG, Lin T, Shokhirev MN, Pinto AFM, Ross DS, Saghatelian A, Panda S, Dow LE, Metallo CM, Shaw RJ. Garcia D, et al. Among authors: saghatelian a. Cell Rep. 2019 Jan 2;26(1):192-208.e6. doi: 10.1016/j.celrep.2018.12.036. Cell Rep. 2019. PMID: 30605676 Free PMC article.
Directed remodeling of the mouse gut microbiome inhibits the development of atherosclerosis.
Chen PB, Black AS, Sobel AL, Zhao Y, Mukherjee P, Molparia B, Moore NE, Aleman Muench GR, Wu J, Chen W, Pinto AFM, Maryanoff BE, Saghatelian A, Soroosh P, Torkamani A, Leman LJ, Ghadiri MR. Chen PB, et al. Among authors: saghatelian a. Nat Biotechnol. 2020 Nov;38(11):1288-1297. doi: 10.1038/s41587-020-0549-5. Epub 2020 Jun 15. Nat Biotechnol. 2020. PMID: 32541956 Free PMC article.
Serine restriction alters sphingolipid diversity to constrain tumour growth.
Muthusamy T, Cordes T, Handzlik MK, You L, Lim EW, Gengatharan J, Pinto AFM, Badur MG, Kolar MJ, Wallace M, Saghatelian A, Metallo CM. Muthusamy T, et al. Among authors: saghatelian a. Nature. 2020 Oct;586(7831):790-795. doi: 10.1038/s41586-020-2609-x. Epub 2020 Aug 12. Nature. 2020. PMID: 32788725 Free PMC article.
ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids.
Patel R, Santoro A, Hofer P, Tan D, Oberer M, Nelson AT, Konduri S, Siegel D, Zechner R, Saghatelian A, Kahn BB. Patel R, et al. Among authors: saghatelian a. Nature. 2022 Jun;606(7916):968-975. doi: 10.1038/s41586-022-04787-x. Epub 2022 Jun 8. Nature. 2022. PMID: 35676490 Free PMC article.
Diet and feeding pattern modulate diurnal dynamics of the ileal microbiome and transcriptome.
Dantas Machado AC, Brown SD, Lingaraju A, Sivaganesh V, Martino C, Chaix A, Zhao P, Pinto AFM, Chang MW, Richter RA, Saghatelian A, Saltiel AR, Knight R, Panda S, Zarrinpar A. Dantas Machado AC, et al. Among authors: saghatelian a. Cell Rep. 2022 Jul 5;40(1):111008. doi: 10.1016/j.celrep.2022.111008. Cell Rep. 2022. PMID: 35793637 Free PMC article.
Intestinal transgene delivery with native E. coli chassis allows persistent physiological changes.
Russell BJ, Brown SD, Siguenza N, Mai I, Saran AR, Lingaraju A, Maissy ES, Dantas Machado AC, Pinto AFM, Sanchez C, Rossitto LA, Miyamoto Y, Richter RA, Ho SB, Eckmann L, Hasty J, Gonzalez DJ, Saghatelian A, Knight R, Zarrinpar A. Russell BJ, et al. Among authors: saghatelian a. Cell. 2022 Aug 18;185(17):3263-3277.e15. doi: 10.1016/j.cell.2022.06.050. Epub 2022 Aug 4. Cell. 2022. PMID: 35931082 Free PMC article.
Time-Restricted Feeding Reduces Atherosclerosis in LDLR KO Mice but Not in ApoE Knockout Mice.
Chaix A, Lin T, Ramms B, Cutler RG, Le T, Lopez C, Miu P, Pinto AFM, Saghatelian A, Playford MP, Mehta NN, Mattson MP, Gordts P, Witztum JL, Panda S. Chaix A, et al. Among authors: saghatelian a. Arterioscler Thromb Vasc Biol. 2024 Sep;44(9):2069-2087. doi: 10.1161/ATVBAHA.124.320998. Epub 2024 Aug 1. Arterioscler Thromb Vasc Biol. 2024. PMID: 39087348
168 results