Kim K - Search Results

1

Endothelial cell CD36 optimizes tissue fatty acid uptake.

Son NH, Basu D, Samovski D, Pietka TA, Peche VS, Willecke F, Fang X, Yu SQ, Scerbo D, Chang HR, Sun F, Bagdasarov S, Drosatos K, Yeh ST, Mullick AE, Shoghi KI, Gumaste N, Kim K, Huggins LA, Lhakhang T, Abumrad NA, Goldberg IJ. Son NH, et al. Among authors: kim k. J Clin Invest. 2018 Oct 1;128(10):4329-4342. doi: 10.1172/JCI99315. Epub 2018 Jul 26. J Clin Invest. 2018. PMID: 30047927 Free PMC article.

2

γ-Secretase Inhibition Lowers Plasma Triglyceride-Rich Lipoproteins by Stabilizing the LDL Receptor.

Kim K, Goldberg IJ, Graham MJ, Sundaram M, Bertaggia E, Lee SX, Qiang L, Haeusler RA, Metzger D, Chambon P, Yao Z, Ginsberg HN, Pajvani UB. Kim K, et al. Cell Metab. 2018 Apr 3;27(4):816-827.e4. doi: 10.1016/j.cmet.2018.02.010. Epub 2018 Mar 22. Cell Metab. 2018. PMID: 29576536 Free PMC article.

3

Adipocyte PHLPP2 inhibition prevents obesity-induced fatty liver.

Kim K, Kang JK, Jung YH, Lee SB, Rametta R, Dongiovanni P, Valenti L, Pajvani UB. Kim K, et al. Nat Commun. 2021 Mar 23;12(1):1822. doi: 10.1038/s41467-021-22106-2. Nat Commun. 2021. PMID: 33758172 Free PMC article.

4

Hepatocyte TLR4 triggers inter-hepatocyte Jagged1/Notch signaling to determine NASH-induced fibrosis.

Yu J, Zhu C, Wang X, Kim K, Bartolome A, Dongiovanni P, Yates KP, Valenti L, Carrer M, Sadowski T, Qiang L, Tabas I, Lavine JE, Pajvani UB. Yu J, et al. Among authors: kim k. Sci Transl Med. 2021 Jun 23;13(599):eabe1692. doi: 10.1126/scitranslmed.abe1692. Sci Transl Med. 2021. PMID: 34162749 Free PMC article.

5

Degradation of PHLPP2 by KCTD17, via a Glucagon-Dependent Pathway, Promotes Hepatic Steatosis.

Kim K, Ryu D, Dongiovanni P, Ozcan L, Nayak S, Ueberheide B, Valenti L, Auwerx J, Pajvani UB. Kim K, et al. Gastroenterology. 2017 Dec;153(6):1568-1580.e10. doi: 10.1053/j.gastro.2017.08.039. Epub 2017 Aug 30. Gastroenterology. 2017. PMID: 28859855 Free PMC article.

6

Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis.

Zhu C, Kim K, Wang X, Bartolome A, Salomao M, Dongiovanni P, Meroni M, Graham MJ, Yates KP, Diehl AM, Schwabe RF, Tabas I, Valenti L, Lavine JE, Pajvani UB. Zhu C, et al. Among authors: kim k. Sci Transl Med. 2018 Nov 21;10(468):eaat0344. doi: 10.1126/scitranslmed.aat0344. Sci Transl Med. 2018. PMID: 30463916 Free PMC article.

7

Liver-selective γ-secretase inhibition ameliorates diet-induced hepatic steatosis, dyslipidemia and atherosclerosis.

Kim K, Yu J, Kang JK, Morrow JP, Pajvani UB. Kim K, et al. Biochem Biophys Res Commun. 2020 Jul 5;527(4):979-984. doi: 10.1016/j.bbrc.2020.04.157. Epub 2020 May 18. Biochem Biophys Res Commun. 2020. PMID: 32439159 Free PMC article.

8

mTORC1-independent Raptor prevents hepatic steatosis by stabilizing PHLPP2.

Kim K, Qiang L, Hayden MS, Sparling DP, Purcell NH, Pajvani UB. Kim K, et al. Nat Commun. 2016 Jan 8;7:10255. doi: 10.1038/ncomms10255. Nat Commun. 2016. PMID: 26743335 Free PMC article.

9

"Free" Raptor - a novel regulator of metabolism.

Kim K, Pajvani UB. Kim K, et al. Cell Cycle. 2016 May 2;15(9):1174-5. doi: 10.1080/15384101.2016.1159835. Cell Cycle. 2016. PMID: 26987027 Free PMC article. No abstract available.

10

Adipocyte-specific blockade of gamma-secretase, but not inhibition of Notch activity, reduces adipose insulin sensitivity.

Sparling DP, Yu J, Kim K, Zhu C, Brachs S, Birkenfeld AL, Pajvani UB. Sparling DP, et al. Among authors: kim k. Mol Metab. 2015 Dec 2;5(2):113-121. doi: 10.1016/j.molmet.2015.11.006. eCollection 2016 Feb. Mol Metab. 2015. PMID: 26909319 Free PMC article.

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